2010
Transmissible encephalopathy agents
Manuelidis L. Transmissible encephalopathy agents. Virulence 2010, 1: 101-104. PMID: 21178425, PMCID: PMC3073180, DOI: 10.4161/viru.1.2.10822.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCattleCattle DiseasesGeographyHumansMicePrion DiseasesPrionsTime FactorsVirulenceConceptsTransmissible spongiform encephalopathiesKuru agentNormal miceRecent transmissionInfectious agentsTissue pathologyTSE agentsDisease latencyVirulence characteristicsNeural cellsSpongiform encephalopathiesPrion hypothesisEpidemic spreadAgentsGeographic regionsEncephalopathyVirulenceSuperinfectionMicePathology
2009
The kuru infectious agent is a unique geographic isolate distinct from Creutzfeldt–Jakob disease and scrapie agents
Manuelidis L, Chakrabarty T, Miyazawa K, Nduom NA, Emmerling K. The kuru infectious agent is a unique geographic isolate distinct from Creutzfeldt–Jakob disease and scrapie agents. Proceedings Of The National Academy Of Sciences Of The United States Of America 2009, 106: 13529-13534. PMID: 19633190, PMCID: PMC2715327, DOI: 10.1073/pnas.0905825106.Peer-Reviewed Original ResearchConceptsSporadic Creutzfeldt-Jakob diseaseCreutzfeldt-Jakob diseaseBovine spongiform encephalopathyBSE agentHuman sporadic Creutzfeldt-Jakob diseaseInfectious agentsEpidemic bovine spongiform encephalopathyTSE agentsScrapie agentTransmissible spongiform encephalopathy agentsSpongiform encephalopathy agentKuru agentLymphoreticular involvementBrain neuropathologySporadic CJDGT1 cellsNormal miceInfected humansNeurodegenerative diseasesDiseaseViral receptorsInfectious neurodegenerative diseasesSheep scrapieSpongiform encephalopathiesHigh levels