Thousands of missed genes found in bacterial genomes and their analysis with COMBREX
Wood DE, Lin H, Levy-Moonshine A, Swaminathan R, Chang YC, Anton BP, Osmani L, Steffen M, Kasif S, Salzberg SL. Thousands of missed genes found in bacterial genomes and their analysis with COMBREX. Biology Direct 2012, 7: 37. PMID: 23111013, PMCID: PMC3534567, DOI: 10.1186/1745-6150-7-37.Peer-Reviewed Original ResearchConceptsProtein-coding genesProkaryotic genome annotationCost of sequencingGenome annotationHypothetical proteinsBacterial genomesProkaryotic genomesShort genesArcady MushegianLikely geneGenesPhenotype informationGenomeHomologPotential targetPathogenic organismsAnnotationSequencingProteinFunction databaseAnnotation methodDramatic reductionGenBankOrganismsPharmaceutical research