2012
Thousands of missed genes found in bacterial genomes and their analysis with COMBREX
Wood DE, Lin H, Levy-Moonshine A, Swaminathan R, Chang YC, Anton BP, Osmani L, Steffen M, Kasif S, Salzberg SL. Thousands of missed genes found in bacterial genomes and their analysis with COMBREX. Biology Direct 2012, 7: 37. PMID: 23111013, PMCID: PMC3534567, DOI: 10.1186/1745-6150-7-37.Peer-Reviewed Original ResearchConceptsProtein-coding genesProkaryotic genome annotationCost of sequencingGenome annotationHypothetical proteinsBacterial genomesProkaryotic genomesShort genesArcady MushegianLikely geneGenesPhenotype informationGenomeHomologPotential targetPathogenic organismsAnnotationSequencingProteinFunction databaseAnnotation methodDramatic reductionGenBankOrganismsPharmaceutical research
2010
COMBREX: a project to accelerate the functional annotation of prokaryotic genomes
Roberts RJ, Chang YC, Hu Z, Rachlin JN, Anton BP, Pokrzywa RM, Choi HP, Faller LL, Guleria J, Housman G, Klitgord N, Mazumdar V, McGettrick MG, Osmani L, Swaminathan R, Tao KR, Letovsky S, Vitkup D, Segrè D, Salzberg SL, Delisi C, Steffen M, Kasif S. COMBREX: a project to accelerate the functional annotation of prokaryotic genomes. Nucleic Acids Research 2010, 39: d11-d14. PMID: 21097892, PMCID: PMC3013729, DOI: 10.1093/nar/gkq1168.Peer-Reviewed Original Research