2021
Comparison of open and a novel closed vitrification system with slow freezing for human ovarian tissue cryopreservation
Sugishita Y, Taylan E, Kawahara T, Shahmurzada B, Suzuki N, Oktay K. Comparison of open and a novel closed vitrification system with slow freezing for human ovarian tissue cryopreservation. Journal Of Assisted Reproduction And Genetics 2021, 38: 2723-2733. PMID: 34398400, PMCID: PMC8581089, DOI: 10.1007/s10815-021-02297-9.Peer-Reviewed Original ResearchConceptsFollicle survivalCortical piecesPrimary folliclesHuman ovarian tissue cryopreservationOvarian tissue cryopreservationCell death pathway activationOvarian cortical piecesPrimordial follicle survivalPrimordial follicle densityHuman ovarian tissueClosed vitrification systemTissue cryopreservationDNA damageOvarian tissueHistological analysisPathway activationApoptosis rateDevice groupSlow freezing
1995
Proliferating Cell Nuclear Antigen Marks the Initiation of Follicular Growth in the Rat1
Oktay K, Schenken R, Nelson J. Proliferating Cell Nuclear Antigen Marks the Initiation of Follicular Growth in the Rat1. Biology Of Reproduction 1995, 53: 295-301. PMID: 7492681, DOI: 10.1095/biolreprod53.2.295.Peer-Reviewed Original ResearchConceptsPCNA expressionPrimary folliclesFollicle growthCell nuclear antigenAntral folliclesFollicular growthPCNA immunoreactivityGranulosa cellsNuclear antigenEarly primary folliclesGranulosa cell layerTransitional folliclesControl ratsAdult ratsPrimordial folliclesSensitive markerPCNA stainingAtretic folliclesRat ovaryOocyte enlargementProliferating Cell Nuclear AntigenEarly signsFolliclesParaffin sectionsPregranulosa cells