2010
Mediation of nonerosive arthritis in a mouse model of lupus by interferon‐α–stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis
Mensah KA, Mathian A, Ma L, Xing L, Ritchlin CT, Schwarz EM. Mediation of nonerosive arthritis in a mouse model of lupus by interferon‐α–stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis. Arthritis & Rheumatism 2010, 62: 1127-1137. PMID: 20131244, PMCID: PMC2854832, DOI: 10.1002/art.27312.Peer-Reviewed Original ResearchConceptsMyeloid dendritic cellsSystemic lupus erythematosusSerum-induced arthritisNZB xBone erosionDendritic cellsOsteoclast precursorsAntibody titersMouse modelAnti-dsDNA antibody titersDNA antibody titersMicrofocal computed tomographyCytokine interferon-alphaEffects of IFNalphaJaccoud's arthritisNonerosive arthritisSLE diseaseJoint inflammationLupus erythematosusAutoimmune diseasesNZW miceSerum administrationInterferon alphaFocal erosionsSLE monocytes
2009
The emerging field of osteoimmunology
Mensah KA, Li J, Schwarz EM. The emerging field of osteoimmunology. Immunologic Research 2009, 45: 100-113. PMID: 19184540, PMCID: PMC2934875, DOI: 10.1007/s12026-009-8093-x.Peer-Reviewed Original ResearchConceptsRheumatoid arthritisAdaptive immune effector cellsImmune effector cellsTreatment of autoimmuneField of osteoimmunologyMetabolic bone diseaseSkeletal systemImmune cell ontogenySubsequent effector functionsBasic science findingsEffector cellsAutoimmune diseasesInflammatory diseasesBone diseaseEffector functionsBone microenvironmentBiologic drugsDiseaseCell ontogenyBone biologyClinical applicationEffector moleculesOsteoimmunologyRecent findingsRecent studies