Implications of Toll-like receptors (TLRs) and their signaling mechanisms in human cancers
Chandrasekar S, Palaniyandi T, Parthasarathy U, Surendran H, Viswanathan S, Wahab M, Baskar G, Natarajan S, Ranjan K. Implications of Toll-like receptors (TLRs) and their signaling mechanisms in human cancers. Pathology - Research And Practice 2023, 248: 154673. PMID: 37453359, DOI: 10.1016/j.prp.2023.154673.Peer-Reviewed Original ResearchToll-like receptorsActivation of TLRsHuman cancersEssential pattern recognition receptorsInnate immune functionNew therapeutic targetsPattern recognition receptorsControl of cancerTLRs 2Inflammatory responseInflammatory microenvironmentEffector functionsImmune functionTherapeutic targetHepatic cancerEpithelial markersCancerHuman lungMost cancersTLR genesReceptorsCancer biomarkersMajor mechanismGene expressionSuch deregulation