2018
Using support vector machines on photoplethysmographic signals to discriminate between hypovolemia and euvolemia
Reljin N, Zimmer G, Malyuta Y, Shelley K, Mendelson Y, Blehar DJ, Darling CE, Chon KH. Using support vector machines on photoplethysmographic signals to discriminate between hypovolemia and euvolemia. PLOS ONE 2018, 13: e0195087. PMID: 29596477, PMCID: PMC5875841, DOI: 10.1371/journal.pone.0195087.Peer-Reviewed Original ResearchConceptsBlood lossTrauma patientsTraditional vital signsLast time pointBlood pressureHemorrhagic shockCombat casualty careBlood withdrawalHealthy volunteersPhotoplethysmographic recordingsHeart rateBlood volumeEuvolemiaVital signsHypovolemiaPercentage changeTime pointsAbsolute changeCasualty carePatientsBattlefield settingsEarly stagesHemorrhageRecordingsHospital
2016
Ventilation-Induced Modulation of Pulse Oximeter Waveforms
Alian AA, Atteya G, Gaal D, Golembeski T, Smith BG, Dai F, Silverman DG, Shelley K. Ventilation-Induced Modulation of Pulse Oximeter Waveforms. Anesthesia & Analgesia 2016, 123: 346-356. PMID: 27284998, DOI: 10.1213/ane.0000000000001377.Peer-Reviewed Original ResearchConceptsSystolic blood pressureArterial pressure waveformBlood volumeFluid resuscitationBlood pressureOnly systolic blood pressurePressure waveformAirway pressure waveformFinger pulse oximetrySubstantial blood lossDynamic preload indicesVenous blood volumeArterial pressure measurementsArterial waveform parametersP-valuePulse oximeter waveformWilcoxon signed-rank testArterial pressureBlood lossBlood transfusionEarly bleedingPediatric patientsPreload indexHemodynamic dataScoliosis surgery
2012
Using Time-Frequency Analysis of the Photoplethysmographic Waveform to Detect the Withdrawal of 900 mL of Blood
Scully CG, Selvaraj N, Romberg FW, Wardhan R, Ryan J, Florian JP, Silverman DG, Shelley KH, Chon KH. Using Time-Frequency Analysis of the Photoplethysmographic Waveform to Detect the Withdrawal of 900 mL of Blood. Anesthesia & Analgesia 2012, 115: 74-81. PMID: 22543068, DOI: 10.1213/ane.0b013e318256486c.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlood PressureBlood Pressure DeterminationBlood Transfusion, AutologousBlood VolumeBlood Volume DeterminationCluster AnalysisConnecticutElectrocardiographyHeart RateHumansHypovolemiaInfrared RaysMalePhotoplethysmographyPredictive Value of TestsRespiratory MechanicsSensitivity and SpecificitySignal Processing, Computer-AssistedTime FactorsConceptsML of bloodArterial blood pressureBlood lossBlood pressureHeart rateHeart rate frequencyBlood withdrawalML blood lossMean percent decreaseBlood volume lossHeart rate componentSignificant changesPhotoplethysmographic waveformSpontaneous breathingTrauma settingCuff measurementsPPG waveformBlood reinfusionHealthy volunteersStandard electrocardiogramBloodEarly detectionEar PPG signalsBaselineConfidence intervals
1997
Arterial–Pulse Oximetry Loops: A New Method of Monitoring Vascular Tone
Shelley K, Bosseau Murray W, Chang D. Arterial–Pulse Oximetry Loops: A New Method of Monitoring Vascular Tone. Journal Of Clinical Monitoring 1997, 13: 223-228. PMID: 9269615, DOI: 10.1023/a:1007361020825.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic alpha-AgonistsAnesthesia, IntravenousArteriesBlood PressureBlood VolumeCalibrationCephalometryDose-Response Relationship, DrugEphedrineFemaleFingersForecastingHeart RateHumansHypotensionIntraoperative ComplicationsMeningiomaMiddle AgedMonitoring, PhysiologicOnline SystemsOximetryPhenylephrinePlethysmographySignal Processing, Computer-AssistedVascular ResistanceVasoconstrictor AgentsVasomotor SystemConceptsPulse oximeter waveformVascular resistanceVascular toneVascular compliancePeripheral vascular complianceVascular compliance changesPeripheral vascular resistanceDose-response curveArterial pressureCase reportArterial waveformClinical informationCompliance changesRelative complianceComplianceTonePhenylephrineOff-line calculation