2015
Symptom-Onset Dosing of Sertraline for the Treatment of Premenstrual Dysphoric Disorder: A Randomized Clinical Trial
Yonkers KA, Kornstein SG, Gueorguieva R, Merry B, Van Steenburgh K, Altemus M. Symptom-Onset Dosing of Sertraline for the Treatment of Premenstrual Dysphoric Disorder: A Randomized Clinical Trial. JAMA Psychiatry 2015, 72: 1037-1044. PMID: 26351969, PMCID: PMC4811029, DOI: 10.1001/jamapsychiatry.2015.1472.Peer-Reviewed Original ResearchConceptsPremenstrual dysphoric disorderSymptom-onset dosingSerotonin reuptake inhibitorsDays of mensesSSRI withdrawalSymptom onsetSymptomatic daysMenstrual cycleClinical trialsDysphoric disorderOutcome measuresScale scoreSRI treatmentTreatment of PMDDClinical Global Impression ScaleAbrupt treatment cessationDepressive Symptomatology-ClinicianTotal DRSP scoresSecondary outcome measuresPrimary outcome measureGlobal Impression ScaleIDS-C scoresUniversity Medical CenterSertraline hydrochlorideBeginning of menses
2005
Efficacy of a New Low-Dose Oral Contraceptive With Drospirenone in Premenstrual Dysphoric Disorder
Yonkers KA, Brown C, Pearlstein TB, Foegh M, Sampson-Landers C, Rapkin A. Efficacy of a New Low-Dose Oral Contraceptive With Drospirenone in Premenstrual Dysphoric Disorder. Obstetrics And Gynecology 2005, 106: 492-501. PMID: 16135578, DOI: 10.1097/01.aog.0000175834.77215.2e.Peer-Reviewed Original ResearchConceptsPremenstrual dysphoric disorderPlacebo groupSymptom scoresDysphoric disorderNew low dose oral contraceptiveLow-dose oral contraceptivesBehavioral symptom scoresActive treatment groupDaily symptom scoresPhysical symptom scoresEthinyl estradiol groupInactive pillsOral contraceptivesEstradiol groupClinical trialsEthinyl estradiolTreatment cyclesTotal Daily RecordI. EfficacyDrospirenoneSymptomsPill formulationDisordersOCP formulationsPlaceboPretreatment pattern of symptom expression in premenstrual dysphoric disorder
Pearlstein T, Yonkers KA, Fayyad R, Gillespie JA. Pretreatment pattern of symptom expression in premenstrual dysphoric disorder. Journal Of Affective Disorders 2005, 85: 275-282. PMID: 15780697, DOI: 10.1016/j.jad.2004.10.004.Peer-Reviewed Original ResearchConceptsPremenstrual dysphoric disorderPMDD symptomsMenstrual cycleDysphoric disorderPatient variabilityIntermittent dosing strategyOnset of menstruationDSM-IV criteriaPatients' durationAnxiety/tensionSertraline treatmentDRSP scoresPatient daysDosing strategiesSevere symptomsDay 2SymptomsTreatment studiesPretreatment patternAnger/irritabilityMood swingsMore daysWomenSymptom expressionTreatment implications
2001
Venlafaxine in the treatment of premenstrual dysphoric disorder.
Freeman E, Rickels K, Yonkers K, Kunz N, McPherson M, Upton G. Venlafaxine in the treatment of premenstrual dysphoric disorder. Obstetrics And Gynecology 2001, 98: 737-44. PMID: 11704162, DOI: 10.1016/s0029-7844(01)01530-7.Peer-Reviewed Original ResearchConceptsPremenstrual dysphoric disorderDaily symptom reportsTreatment of premenstrual dysphoric disorderDysphoric disorderHamilton Rating Scale for DepressionPremenstrual dysphoric disorder treatmentDSR scoresEfficacy of long-term maintenance treatmentSafety of venlafaxineFlexible-dose trialNew-generation antidepressantsLong-term maintenance treatmentDouble-blind treatmentTreatment cyclesPremenstrual symptom scoresVenlafaxine doseVenlafaxine treatmentSymptom reductionSymptom remissionInhibit serotoninNorepinephrine reuptakePMDD symptomsVenlafaxineSymptom reportingCyclic disorder