2018
Functional connectivity of PAG with core limbic system and laryngeal cortico-motor structures during human phonation
Galgano J, Pantazatos S, Allen K, Yanagihara T, Hirsch J. Functional connectivity of PAG with core limbic system and laryngeal cortico-motor structures during human phonation. Brain Research 2018, 1707: 184-189. PMID: 30500402, PMCID: PMC7434632, DOI: 10.1016/j.brainres.2018.11.040.Peer-Reviewed Original ResearchConceptsPeriaqueductal gray regionPsychophysiological interaction analysisFunctional connectivityDiffusion tensor imaging (DTI) analysisTrend-level evidenceNeural mechanismsBilateral auditory corticesGreater functional connectivityAmygdala couplingWhole-brain resultsDorsomedial prefrontal cortexLimbic systemMotor areaAmygdala clustersAuditory cortexLaryngeal musculatureHealthy adultsPrefrontal cortexNeuroimaging studiesNeural activityVoice disordersStructural connectivityGray regionCortexMovement paradigm
2011
Selective Reduction in Neural Responses to High Calorie Foods Following Gastric Bypass Surgery
Ochner CN, Kwok Y, Conceição E, Pantazatos SP, Puma LM, Carnell S, Teixeira J, Hirsch J, Geliebter A. Selective Reduction in Neural Responses to High Calorie Foods Following Gastric Bypass Surgery. Annals Of Surgery 2011, 253: 502-507. PMID: 21169809, PMCID: PMC3128512, DOI: 10.1097/sla.0b013e318203a289.Peer-Reviewed Original ResearchConceptsRYGB surgeryHigh-calorie foodsPostsurgical reductionFood cuesCaloric intakeLow-calorie food cuesCommon bariatric proceduresPost-RYGB surgeryGastric bypass surgeryBrain activationNeural activationVerbal rating scaleCaloric densityNeural responsesMesolimbic reward pathwayFunctional magnetic resonance imagingMagnetic resonance imagingMechanism of actionMalabsorptive mechanismsBariatric proceduresGastric bypassBypass surgeryFemale patientsGut peptidesPostbariatric surgery
2008
Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli
Rosenbaum M, Sy M, Pavlovich K, Leibel RL, Hirsch J. Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli. Journal Of Clinical Investigation 2008, 118: 2583-2591. PMID: 18568078, PMCID: PMC2430499, DOI: 10.1172/jci35055.Peer-Reviewed Original ResearchConceptsMiddle frontal gyrusNeural activityFood cuesFrontal gyrusFood-related visual cuesWeight lossFood intakeWeight loss-induced changesVisual food cuesVisual food stimuliMiddle temporal gyrusRelative leptin deficiencyWeight-reduced stateDaily subcutaneous injectionsBody weight maintenanceCognitive controlFood stimuliTemporal gyrusVisual cuesLeptin deficiencyObese subjectsWeight maintenanceLingual gyrusClinical managementFunctional MRI
2007
Repeated Exposure to Media Violence Is Associated with Diminished Response in an Inhibitory Frontolimbic Network
Kelly CR, Grinband J, Hirsch J. Repeated Exposure to Media Violence Is Associated with Diminished Response in an Inhibitory Frontolimbic Network. PLOS ONE 2007, 2: e1268. PMID: 18060062, PMCID: PMC2092389, DOI: 10.1371/journal.pone.0001268.Peer-Reviewed Original ResearchMeSH KeywordsAdultAggressionAmygdalaAnalysis of VarianceFemaleFrontal LobeHumansLimbic SystemMaleMass MediaViolenceConceptsFunctional magnetic resonance imagingRight lateral orbitofrontal cortexMagnetic resonance imagingLateral orbitofrontal cortexDiminished responsivenessDiminished responseShort-term exposureResonance imagingFrontolimbic networkOrbitofrontal cortexCortical networksNovel findingsExposureResponseCortex