2012
Conceptual representations of perceptual knowledge
Smith EE, Myers N, Sethi U, Pantazatos S, Yanagihara T, Hirsch J. Conceptual representations of perceptual knowledge. Cognitive Neuropsychology 2012, 29: 237-248. PMID: 22994286, PMCID: PMC3516296, DOI: 10.1080/02643294.2012.706218.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusFunctional magnetic resonance imagingFusiform gyrusPerceptual propertiesPerceptual knowledgeLeft inferior frontal gyrusLeft fusiform gyrusMiddle temporal gyrusPerceptual processingAmodal processesModality-specific mannerSemantic memoryBehavioral performanceFrontal gyrusThompson-SchillConceptual representationKan et alVerbal statementsGyrusParticipantsProcessingMagnetic resonance imagingRepresentationBarsalouMemoryNeural systems for speech and song in autism
Lai G, Pantazatos SP, Schneider H, Hirsch J. Neural systems for speech and song in autism. Brain 2012, 135: 961-975. PMID: 22298195, PMCID: PMC3286324, DOI: 10.1093/brain/awr335.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAgingAnisotropyAttentionAutistic DisorderBrainChildDiffusion Tensor ImagingFemaleFunctional LateralityHead MovementsHumansImage Processing, Computer-AssistedInterview, PsychologicalLanguageMagnetic Resonance ImagingMaleMusicNerve NetNeural PathwaysNeuropsychological TestsPhotic StimulationRecruitment, NeurophysiologicalSpeechYoung AdultConceptsInferior frontal gyrusLeft inferior frontal gyrusFrontal gyrusAutistic childrenNeural systemsArcuate fasciculusFunctional magnetic resonanceSuperior temporal gyrusAge-matched control childrenLeft arcuate fasciculusPassive auditory stimulationMusic abilityLanguage disabilitySong conditionTemporal gyrusSpeech stimulationAuditory stimulationAutismFunctional connectivityNeural organizationBrain regionsSpeechControl childrenGyrusAutistic
2009
Reperfusion normalizes motor activation patterns in large‐vessel disease
Chmayssani M, Lazar RM, Hirsch J, Marshall RS. Reperfusion normalizes motor activation patterns in large‐vessel disease. Annals Of Neurology 2009, 65: 203-208. PMID: 19259970, PMCID: PMC2653600, DOI: 10.1002/ana.21554.Peer-Reviewed Original ResearchConceptsMotor activation patternsVasomotor reactivityActivation patternsInterest analysisIpsilateral motor activationLarge vessel diseaseNormal neurological functionHealthy control subjectsHigh-grade stenosisBlood oxygen level-dependent (BOLD) signalNormal blood flowDynamic functional reorganizationLevel-dependent signalFunctional magnetic resonanceRepeated-measures analysisHemodynamic failureHemodynamic impairmentRevascularization proceduresIpsilateral hemisphereNeurological functionControl subjectsClinical consequencesBlood flowFunctional reorganizationSpontaneous resolution
2008
The dynamics of deductive reasoning: An fMRI investigation
Rodriguez-Moreno D, Hirsch J. The dynamics of deductive reasoning: An fMRI investigation. Neuropsychologia 2008, 47: 949-961. PMID: 18835284, DOI: 10.1016/j.neuropsychologia.2008.08.030.Peer-Reviewed Original ResearchConceptsDeductive reasoningReasoning processParietal regionsEvent-related fMRISupramodal networkPrevious imaging studiesNeural correlatesFMRI investigationOccipital complexLanguage areasBilateral caudate nucleusInformation processingReasoningSecond premiseImaging studiesTraditional focusCaudate nucleusSubstantive differencesFMRISubsequent conclusionsTime courseScientific investigationPhilosophical discussionCorrelatesTime pointsNeural Integration of Top-Down Spatial and Feature-Based Information in Visual Search
Egner T, Monti JM, Trittschuh EH, Wieneke CA, Hirsch J, Mesulam M. Neural Integration of Top-Down Spatial and Feature-Based Information in Visual Search. Journal Of Neuroscience 2008, 28: 6141-6151. PMID: 18550756, PMCID: PMC6670545, DOI: 10.1523/jneurosci.1262-08.2008.Peer-Reviewed Original ResearchConceptsCue informationVisual searchActivation gainVisual search targetBlood oxygenation level-dependent (BOLD) responseSpatial cue informationLevel-dependent responsesSearch onsetDown biasingSpatial expectancyOculomotor planningIntraparietal sulcusSearch targetSalience mapBOLD responseSearch templateCingulate regionsNeural integrationTarget featuresHuman brainTarget locationSearch performance
2007
Brain Activity Associated With Stimulation Therapy of the Visual Borderzone in Hemianopic Stroke Patients
Marshall RS, Ferrera JJ, Barnes A, Xian Zhang, O'Brien KA, Chmayssani M, Hirsch J, Lazar RM. Brain Activity Associated With Stimulation Therapy of the Visual Borderzone in Hemianopic Stroke Patients. Neurorehabilitation And Neural Repair 2007, 22: 136-144. PMID: 17698955, DOI: 10.1177/1545968307305522.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PhysiologicalAdultAgedAttentionBrainBrain MappingCerebrovascular CirculationFemaleFunctional LateralityHemianopsiaHumansMagnetic Resonance ImagingMaleMiddle AgedNeuronal PlasticityPhotic StimulationPhysical Therapy ModalitiesStrokeTreatment OutcomeVisual PathwaysVisual PerceptionConceptsVisual restoration therapyRestoration therapyHemianopic patientsAnterior cingulateHemianopic stroke patientsHigher-order visual areasBilateral anterior cingulateBilateral basal gangliaHome-based treatment programDorsolateral frontal cortexBlood oxygen level-dependent activityBrain activityFunctional magnetic resonance imagingMagnetic resonance imagingBrain Activity AssociatedCondition interactionLevel-dependent activityStroke patientsBasal gangliaBrain injuryStimulation therapyFrontal cortexMiddle temporal regionsRepetitive stimulationVisual therapyNeural Dynamics of Rejection Sensitivity
Kross E, Egner T, Ochsner K, Hirsch J, Downey G. Neural Dynamics of Rejection Sensitivity. Journal Of Cognitive Neuroscience 2007, 19: 945-956. PMID: 17536965, DOI: 10.1162/jocn.2007.19.6.945.Peer-Reviewed Original ResearchConceptsRejection sensitivityCognitive controlRS individualsDorsal frontal regionsFunctional magnetic resonanceThemes of rejectionRejection stimuliAffective stimuliEmotional appraisalEmotional processingNegative valenceIndividual differencesPrefrontal structuresNeural dynamicsDistress ratingsFrontal regionsRepresentational paintingsBrain regionsR participantsStimuliPositive imageDifferential recruitmentIndividual responsesParticipantsInterest levelCortical activation during word processing in late bilinguals: Similarities and differences as revealed by functional magnetic resonance imaging
Marian V, Shildkrot Y, Blumenfeld HK, Kaushanskaya M, Faroqi-Shah Y, Hirsch J. Cortical activation during word processing in late bilinguals: Similarities and differences as revealed by functional magnetic resonance imaging. Journal Of Clinical And Experimental Neuropsychology 2007, 29: 247-265. PMID: 17454346, DOI: 10.1080/13803390600659376.Peer-Reviewed Original ResearchMeSH KeywordsAcoustic StimulationAdolescentAdultCerebral CortexData Interpretation, StatisticalFemaleFrontal LobeFunctional LateralityHumansImage Processing, Computer-AssistedLanguage TestsMagnetic Resonance ImagingMaleMental ProcessesMultilingualismNerve NetOccipital LobeSpeech PerceptionTemporal LobeConceptsInferior frontal gyrusLeft inferior frontal gyrusFunctional magnetic resonance imagingLexical processingSuperior temporal gyrusSecond languageCenter of activationCortical activationRight inferior frontal gyrusRussian-English bilingualsCortical organizationSimilar cortical networksLate bilingualsTranslation equivalentsOrthographic processingPhonological processingSame languageWord processingInferior frontalFrontal gyrusSupramarginal gyrusLanguageDifferent wordsTemporal gyrusBilinguals
2006
Facial Emotion Recognition after Curative Nondominant Temporal Lobectomy in Patients with Mesial Temporal Sclerosis
McClelland S, Garcia RE, Peraza DM, Shih TT, Hirsch LJ, Hirsch J, Goodman RR. Facial Emotion Recognition after Curative Nondominant Temporal Lobectomy in Patients with Mesial Temporal Sclerosis. Epilepsia 2006, 47: 1337-1342. PMID: 16922878, DOI: 10.1111/j.1528-1167.2006.00557.x.Peer-Reviewed Original ResearchConceptsMesial temporal sclerosisAnteromedial temporal lobectomyTemporal lobe epilepsyTLE onsetTemporal sclerosisTemporal lobectomyRight amygdalaEarly-onset patientsLate-onset patientsEarly-onset groupLate-onset groupAmygdalar damageAge 6 yearsFER impairmentPostsurgical populationLobe epilepsyLeft-hemisphere language dominancePreoperative MRIPatientsFrightened expressionImpaired facial emotion recognitionLobectomySclerosisAmygdalaOnset
2005
Cognitive control mechanisms resolve conflict through cortical amplification of task-relevant information
Egner T, Hirsch J. Cognitive control mechanisms resolve conflict through cortical amplification of task-relevant information. Nature Neuroscience 2005, 8: 1784-1790. PMID: 16286928, DOI: 10.1038/nn1594.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionBehaviorBrain MappingCerebral CortexCerebrovascular CirculationCognitionConflict, PsychologicalDecision MakingFemaleFunctional LateralityHumansMagnetic Resonance ImagingMaleNerve NetNeural PathwaysNeuropsychological TestsPattern Recognition, VisualPhotic StimulationPrefrontal CortexReaction TimeVisual CortexVolitionConceptsTask-relevant informationCognitive control mechanismsTask-irrelevant informationCognitive controlTask-relevant stimulus informationCognitive control systemConflict resolutionDorsolateral prefrontal cortexHuman visual cortexAttentional biasingFace processingPerceptual processingFace stimuliStroop taskNeural representationStimulus informationResponse tendenciesOccurrence of conflictsHigh conflictPrefrontal cortexProminent modelsCortical responsesTrial levelCortical amplificationVisual cortexFunctional Specialization within the Medial Frontal Gyrus for Perceptual Go/No-Go Decisions Based on What, When, and Where Related Information: An fMRI Study
Talati A, Hirsch J. Functional Specialization within the Medial Frontal Gyrus for Perceptual Go/No-Go Decisions Based on What, When, and Where Related Information: An fMRI Study. Journal Of Cognitive Neuroscience 2005, 17: 981-993. PMID: 16102231, DOI: 10.1162/0898929054475226.Peer-Reviewed Original ResearchHuman Cortical Specialization for Food: a Functional Magnetic Resonance Imaging Investigation 1
St-Onge MP, Sy M, Heymsfield SB, Hirsch J. Human Cortical Specialization for Food: a Functional Magnetic Resonance Imaging Investigation 1. Journal Of Nutrition 2005, 135: 1014-1018. PMID: 15867274, DOI: 10.1093/jn/135.5.1014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionBody WeightBrain MappingCerebral CortexFemaleFunctional LateralityHumansMagnetic Resonance ImagingMaleMiddle AgedPhotic StimulationTouchConceptsFunctional magnetic resonance imagingNonfood itemsFood-related stimuliSuperior temporal gyrusAppreciation of foodFood-related behaviorsRight-handed manVisual foodNeural substratesCortical specializationSpecific sensory stimuliTemporal gyrusPresentation of foodCognitive functionAnterior cingulateSensory stimuliNeural systemsParahippocampal gyrusCortical responsesCortical pathwaysBrain regionsNonfoodGyrusStimuliItemsThe neural correlates and functional integration of cognitive control in a Stroop task
Egner T, Hirsch J. The neural correlates and functional integration of cognitive control in a Stroop task. NeuroImage 2005, 24: 539-547. PMID: 15627596, DOI: 10.1016/j.neuroimage.2004.09.007.Peer-Reviewed Original ResearchConceptsCognitive controlConflict adaptationPsychophysiological interaction analysisStroop taskNeural correlatesFrontal gyrusPrefrontal cortexDistinct fronto-parietal networksEvent-related fMRI dataLow-conflict trialsHigh-conflict trialsFronto-parietal networkLateral prefrontal cortexMiddle frontal gyrusBilateral inferior frontalSuperior frontal gyrusContext-specific modulationInterference taskResponse conflictCognitive tasksConflict effectMotor processesInferior frontalNeural substratesTask performance
2000
Visual Function and Brain Organization in Non-decussating Retinal–Fugal Fibre Syndrome
Victor J, Apkarian P, Hirsch J, Conte M, Packard M, Relkin N, Kim K, Shapley R. Visual Function and Brain Organization in Non-decussating Retinal–Fugal Fibre Syndrome. Cerebral Cortex 2000, 10: 2-22. PMID: 10639391, DOI: 10.1093/cercor/10.1.2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBrain MappingContrast SensitivityElectroencephalographyFemaleFunctional LateralityHumansInfantMagnetic Resonance ImagingMotion PerceptionNeuronal PlasticityOptic ChiasmOptic Nerve DiseasesPhotic StimulationRetinaSyndromeTwins, DizygoticVisual CortexVisual PathwaysVisual PerceptionConceptsVisual functionIpsilateral primary visual cortexExtensive bilateral activationMagnetic resonance imaging studyNormal visual behaviorPrimary visual cortexResonance imaging studyFunctional magnetic resonance imaging studyPrestriate areasVisual namingOcular instabilityRetinal projectionsStriate cortexBilateral activationVisual cortexVisual pathwayImaging studiesContrast sensitivityContralateral representationElectrophysiological investigationsEye mapSimple visual stimuliFunctional neuroimagingPatientsBrain organization