A translational bridge between mouse and human models of learned safety
Pollak DD, Rogan MT, Egner T, Perez DL, Yanagihara TK, Hirsch J. A translational bridge between mouse and human models of learned safety. Annals Of Medicine 2010, 42: 127-134. PMID: 20121549, DOI: 10.3109/07853890903583666.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmygdalaAnimalsAvoidance LearningConditioning, ClassicalDiffusion Tensor ImagingFearFemaleHumansMagnetic Resonance ImagingMaleMicePrefrontal CortexPupilTranslational Research, BiomedicalConceptsDorsolateral prefrontal cortexNeural circuitryPrefrontal cortexAnimal experimentsTranslational bridgeFunctional magnetic resonanceParallel groupSafety signalsPupillary constrictionNoxious stimuliUnderlying neural circuitryHuman studiesExperimental animalsHuman modelNeural connectionsAnimal protocolsMiceCaudate responseNeutral stimuliNeural responsesNeural substratesDiffusion tensorAmygdalaCortexMolecular mechanisms