2013
Sleep restriction increases the neuronal response to unhealthy food in normal-weight individuals
St-Onge M, Wolfe S, Sy M, Shechter A, Hirsch J. Sleep restriction increases the neuronal response to unhealthy food in normal-weight individuals. International Journal Of Obesity 2013, 38: 411-416. PMID: 23779051, PMCID: PMC3883872, DOI: 10.1038/ijo.2013.114.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingFood stimuliRight insulaUnhealthy foodsUnhealthy food stimuliNormal-weight individualsMiddle temporal gyrusLevel-dependent activityInferior parietal lobuleSuperior frontal gyrusInsula activityFrontal gyrusGreater activationNeural mechanismsTemporal gyrusParietal lobuleFood intakeOrbitofrontal cortexRestricted sleepSame stimuliNeuronal responsesSleep restrictionNeural systemsBrain rewardShort sleep duration
2012
Conceptual representations of perceptual knowledge
Smith EE, Myers N, Sethi U, Pantazatos S, Yanagihara T, Hirsch J. Conceptual representations of perceptual knowledge. Cognitive Neuropsychology 2012, 29: 237-248. PMID: 22994286, PMCID: PMC3516296, DOI: 10.1080/02643294.2012.706218.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusFunctional magnetic resonance imagingFusiform gyrusPerceptual propertiesPerceptual knowledgeLeft inferior frontal gyrusLeft fusiform gyrusMiddle temporal gyrusPerceptual processingAmodal processesModality-specific mannerSemantic memoryBehavioral performanceFrontal gyrusThompson-SchillConceptual representationKan et alVerbal statementsGyrusParticipantsProcessingMagnetic resonance imagingRepresentationBarsalouMemoryDecoding Unattended Fearful Faces with Whole-Brain Correlations: An Approach to Identify Condition-Dependent Large-Scale Functional Connectivity
Pantazatos SP, Talati A, Pavlidis P, Hirsch J. Decoding Unattended Fearful Faces with Whole-Brain Correlations: An Approach to Identify Condition-Dependent Large-Scale Functional Connectivity. PLOS Computational Biology 2012, 8: e1002441. PMID: 22479172, PMCID: PMC3315448, DOI: 10.1371/journal.pcbi.1002441.Peer-Reviewed Original ResearchConceptsFearful facesEmotional expressionBilateral middle temporal gyrusThreat-related stimuliUnattended fearful facesLarge-scale functional connectivityMultiple functional connectionsFunctional magnetic resonanceWhole-brain patternsMiddle temporal gyrusWhole-brain correlationActive research goalNeutral facesEmotion processingFear perceptionImplicit fearImplicit presentationAngular gyrusChance accuracyTemporal gyrusBrain activityFace presentationPrefrontal cortexParietal regionsFunctional connectivityCortical functional connectivity decodes subconscious, task-irrelevant threat-related emotion processing
Pantazatos SP, Talati A, Pavlidis P, Hirsch J. Cortical functional connectivity decodes subconscious, task-irrelevant threat-related emotion processing. NeuroImage 2012, 61: 1355-1363. PMID: 22484206, PMCID: PMC3393600, DOI: 10.1016/j.neuroimage.2012.03.051.Peer-Reviewed Original ResearchConceptsFunctional connectivityAffective stimuliCortical-subcortical functional connectivityFearful face processingFear-related stimuliAmygdala functional connectivityMiddle temporal gyrusCortical structuresKey limbic regionsFace processingEmotion processingFear conditionFear processingSubconscious processingAngular gyrusTemporal gyrusCortical functional connectivityRight amygdalaLimbic regionsFC featuresStimuliGyrusProcessingTraining dataPrecuneus
2008
Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli
Rosenbaum M, Sy M, Pavlovich K, Leibel RL, Hirsch J. Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli. Journal Of Clinical Investigation 2008, 118: 2583-2591. PMID: 18568078, PMCID: PMC2430499, DOI: 10.1172/jci35055.Peer-Reviewed Original ResearchConceptsMiddle frontal gyrusNeural activityFood cuesFrontal gyrusFood-related visual cuesWeight lossFood intakeWeight loss-induced changesVisual food cuesVisual food stimuliMiddle temporal gyrusRelative leptin deficiencyWeight-reduced stateDaily subcutaneous injectionsBody weight maintenanceCognitive controlFood stimuliTemporal gyrusVisual cuesLeptin deficiencyObese subjectsWeight maintenanceLingual gyrusClinical managementFunctional MRI
2005
fMRI reveals large-scale network activation in minimally conscious patients
Schiff N, Rodriguez-Moreno D, Kamal A, Kim K, Giacino J, Plum F, Hirsch J. fMRI reveals large-scale network activation in minimally conscious patients. Neurology 2005, 64: 514-523. PMID: 15699384, DOI: 10.1212/01.wnl.0000150883.10285.44.Peer-Reviewed Original ResearchMeSH KeywordsAcoustic StimulationAdultAttentionAuditory CortexAwarenessCerebral HemorrhageCraniocerebral TraumaEncephalomalaciaFixation, OcularHumansLanguageMagnetic Resonance ImagingMalePersistent Vegetative StatePhysical StimulationSomatosensory CortexTemporal LobeTouchVerbal BehaviorWounds, NonpenetratingConceptsCognitive functionCortical activityLanguage-related tasksResidual cognitive functionMiddle temporal gyrusTactile stimulationMeaningless stimuliActive cortical networkConscious stateLanguage stimulationNeurobiological correlatesLanguage functionTemporal gyrusBehavioral evidenceMCS patientsCortical systemsLinguistic contentAuditory stimulationCortical networksLanguage processingCerebral networksNetwork activationCortical responsesCommunication abilityFMRI maps