2023
Complete genome sequences of twelve strains of Leptospira interrogans isolated from humans in Sri Lanka
Senavirathna I, Jayasundara D, Warnasekara J, Matthias M, Vinetz J, Agampodi S. Complete genome sequences of twelve strains of Leptospira interrogans isolated from humans in Sri Lanka. Infection Genetics And Evolution 2023, 113: 105462. PMID: 37301334, DOI: 10.1016/j.meegid.2023.105462.Peer-Reviewed Original Research
2022
Culture-Independent Detection and Identification of Leptospira Serovars
Matthias M, Lubar A, Acharige S, Chaiboonma K, Pilau N, Marroquin A, Jayasundara D, Agampodi S, Vinetz J. Culture-Independent Detection and Identification of Leptospira Serovars. Microbiology Spectrum 2022, 10: e02475-22. PMID: 36445143, PMCID: PMC9769591, DOI: 10.1128/spectrum.02475-22.Peer-Reviewed Original ResearchConceptsPublic health importanceProspective studyFatal diseaseHealth importanceOutbreak investigationSequence typingDog urine samplesCulture-independent assaysEnvironmental surveillance studyMultilocus sequence typingPulsed-field gel electrophoresisSurveillance studyGroup IIHuman leptospirosisPrognostic testSpecific real-time qPCRClinical settingGroup ILeptospira serovarsReal-time qPCRDiagnostic testsSerum samplesUrine samplesDiagnostic specificityLeptospirosis
2021
Next-Generation Sequencing Analysis of Pathogenic Leptospira: A Way Forward for Understanding Infectious Disease Dynamics in Low/Middle-Income, Disease-Endemic Settings.
Agampodi SB, Vinetz JM. Next-Generation Sequencing Analysis of Pathogenic Leptospira: A Way Forward for Understanding Infectious Disease Dynamics in Low/Middle-Income, Disease-Endemic Settings. American Journal Of Tropical Medicine And Hygiene 2021, 104: 1625-1627. PMID: 33755589, PMCID: PMC8103479, DOI: 10.4269/ajtmh.20-1518.Peer-Reviewed Original Research
2018
Experimental Infection of Rattus norvegicus by the Group II Intermediate Pathogen, Leptospira licerasiae.
Fernandez C, Lubar AA, Vinetz JM, Matthias MA. Experimental Infection of Rattus norvegicus by the Group II Intermediate Pathogen, Leptospira licerasiae. American Journal Of Tropical Medicine And Hygiene 2018, 99: 275-280. PMID: 29943708, PMCID: PMC6090328, DOI: 10.4269/ajtmh.17-0844.Peer-Reviewed Original ResearchConceptsOral routeHuman seroreactivitySprague-Dawley ratsRoute of infectionExperimental infection modelQuantitative polymerase chain reactionTranscutaneous routeGastric gavageParenteral inoculationClinical historyPolymerase chain reactionRenal colonizationGroup IIKidney tissuePeruvian Amazon cityExperimental infectionInfectionInfection modelChain reactionSeroreactivityHigh rateRatsReservoir hostsAmazon cityGavage