2021
12 Novel clonal groups of Leptospira infecting humans in multiple contrasting epidemiological contexts in Sri Lanka
Jayasundara D, Senavirathna I, Warnasekara J, Gamage C, Siribaddana S, Kularatne SAM, Matthias M, Mariet JF, Picardeau M, Agampodi S, Vinetz J. 12 Novel clonal groups of Leptospira infecting humans in multiple contrasting epidemiological contexts in Sri Lanka. PLOS Neglected Tropical Diseases 2021, 15: e0009272. PMID: 33735202, PMCID: PMC8009393, DOI: 10.1371/journal.pntd.0009272.Peer-Reviewed Original ResearchConceptsClonal groupsAcute kidney injuryL. interrogansMajor clinical challengeGlobal disease threatsLeptospira speciesL. interrogans infectionKidney injuryLiver impairmentCardiovascular involvementL. borgpeterseniiClinical presentationProspective studyClinical severityClinical challengePathogenic Leptospira speciesAnnual epidemicsUbiquitous zoonotic diseaseNew serogroupEpidemiological contextZoonotic diseaseCulture isolationLeptospiral culturesL. weiliiLeptospira diversity
2001
Leptospirosis
Vinetz J. Leptospirosis. Current Opinion In Infectious Diseases 2001, 14: 527-538. PMID: 11964872, DOI: 10.1097/00001432-200110000-00005.Peer-Reviewed Original ResearchConceptsPopulation-based studyViral hemorrhagic feverImportant zoonotic diseasePulmonary hemorrhageFebrile syndromeLethal complicationTyphoid vaccineClinical expressionLeptospiral geneHemorrhagic feverLeptospirosis vaccineInfectious diseasesLeptospirosisLeptospira spDiseaseVaccineZoonotic diseaseMammalian reservoir hostsLeptospiral strainsRecent reportsLeptospira genomeReservoir hostsPoor correlationComplicationsHemorrhage