2003
γδ T Cells Provide an Early Source of Interferon γ in Tumor Immunity
Gao Y, Yang W, Pan M, Scully E, Girardi M, Augenlicht LH, Craft J, Yin Z. γδ T Cells Provide an Early Source of Interferon γ in Tumor Immunity. Journal Of Experimental Medicine 2003, 198: 433-442. PMID: 12900519, PMCID: PMC2194096, DOI: 10.1084/jem.20030584.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsImmunity, CellularInterferon-gammaInterleukin-12Lymphocyte ActivationMiceMice, Inbred C57BLMice, KnockoutNeoplasm TransplantationNeoplasms, ExperimentalReceptors, Antigen, T-Cell, alpha-betaReceptors, Antigen, T-Cell, gamma-deltaT-Lymphocyte SubsetsTransplantation ChimeraTumor Cells, CulturedConceptsGammadelta T cellsAlphabeta T cellsT cellsTumor immunityIFN-gammaHigh incidenceGammadelta T cell-deficient miceImpaired IFN-gamma productionT cell-deficient miceTumor developmentCell-deficient miceBone marrow chimerasΓδ T cellsIFN-gamma productionSite of tumorT cell repertoireWild-type miceChemical carcinogen methylcholanthreneMelanoma cell line B16B16 melanoma cellsTumor lysateCarcinogen methylcholanthreneTumor immunosurveillanceInterferon γSuch mice
2000
Roles of Fas and Fas ligand during mammary gland remodeling
Song J, Sapi E, Brown W, Nilsen J, Tartaro K, Kacinski B, Craft J, Naftolin F, Mor G. Roles of Fas and Fas ligand during mammary gland remodeling. Journal Of Clinical Investigation 2000, 106: 1209-1220. PMID: 11086022, PMCID: PMC381435, DOI: 10.1172/jci10411.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApoptosisBlotting, WesternCaspase 3CaspasesCell LineCulture MediaCulture Media, Serum-FreeDexamethasoneEpithelial CellsFas Ligand ProteinFas ReceptorFemaleGene ExpressionHumansMammary Glands, AnimalMembrane GlycoproteinsMiceMice, Inbred BALB CMice, Inbred C3HMice, Inbred MRL lprMice, KnockoutPregnancyPregnancy, AnimalRNA, MessengerConceptsMammary epithelial cellsFas/FasL signalsMouse mammary epithelial cellsMammary gland remodelingFasL proteinApoptotic cellsEpithelial cellsInduction of apoptosisAccumulation of cellsSubsequent neoplastic developmentRole of FasMammary gland tissueFasL signalsMammary tissueCell deathExpression of FasFas-FasL interactionMouse mammary tissueMammary cellsCaspase-3Autocrine inductionFas ligandMammary epitheliumNeoplastic developmentTumor development