2023
Baseline platelet serotonin in a multi-site treatment study of depression in veterans administration patients: Distribution and effects of demographic variables and serotonin reuptake inhibitors
Anderson G, Ramsey C, Lynch K, Gelernter J, Oslin D. Baseline platelet serotonin in a multi-site treatment study of depression in veterans administration patients: Distribution and effects of demographic variables and serotonin reuptake inhibitors. Journal Of Affective Disorders 2023, 327: 368-377. PMID: 36754092, DOI: 10.1016/j.jad.2023.02.017.Peer-Reviewed Original ResearchConceptsReuptake inhibitorsVeterans Administration patientsTreatment studiesSubset of patientsNorepinephrine reuptake inhibitorsCross-sectional studyEffect of ageDose adjustmentAfrican American individualsDemographic variablesMean plateletDrug exposurePlatelet serotoninSerotonin valuesPatientsClinical implicationsHealth recordsMale groupSSRIsDepressionPlateletsEuropean AmericansInhibitorsSex differencesGroup means
2015
The Research Domain Criteria (RDoC) Project and Studies of Risk and Resilience in Maltreated Children
Kaufman J, Gelernter J, Hudziak JJ, Tyrka AR, Coplan JD. The Research Domain Criteria (RDoC) Project and Studies of Risk and Resilience in Maltreated Children. Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 54: 617-625. PMID: 26210330, PMCID: PMC4515569, DOI: 10.1016/j.jaac.2015.06.001.Peer-Reviewed Original ResearchConceptsResearch Domain Criteria projectNeural circuitsSubset of patientsRelevant animal modelsOnset of psychopathologyStress-related mechanismsClinical studiesStandard interventionAnimal modelsClinical implicationsMental disordersMaltreated childrenNeural circuitryTranslational researchPrecision medicinePsychiatric nomenclaturePatientsChildrenRDoC projectRDoC frameworkNeurobiological measuresRDoC initiativeRiskUltimate long-term goalStudy of risk