2011
Strong Association of the Alcohol Dehydrogenase 1B Gene (ADH1B) with Alcohol Dependence and Alcohol-Induced Medical Diseases
Li D, Zhao H, Gelernter J. Strong Association of the Alcohol Dehydrogenase 1B Gene (ADH1B) with Alcohol Dependence and Alcohol-Induced Medical Diseases. Biological Psychiatry 2011, 70: 504-512. PMID: 21497796, PMCID: PMC3142297, DOI: 10.1016/j.biopsych.2011.02.024.Peer-Reviewed Original ResearchConceptsAlcohol dependenceAlcohol dehydrogenase 1B (ADH1B) geneMedical diseasesAlcohol-induced liver diseaseStrong associationCertain Asian populationsRandom-effects modelADH1B geneLarger ORsLiver diseaseSubgroup analysisLarger sample sizeDrug dependenceSignificant associationSubstance dependenceMultiple ethnic populationsRecessive modelAsian populationsDisease
2010
Meta-Analysis of 15 Genome-Wide Linkage Scans of Smoking Behavior
Han S, Gelernter J, Luo X, Yang BZ. Meta-Analysis of 15 Genome-Wide Linkage Scans of Smoking Behavior. Biological Psychiatry 2010, 67: 12-19. PMID: 19819424, PMCID: PMC2975396, DOI: 10.1016/j.biopsych.2009.08.028.Peer-Reviewed Original ResearchConceptsSmoking behaviorGenome-wide suggestive linkageGenome-wide linkage scanSubgroup analysisGenome scan resultsScan resultsLinkage scanSuggestive linkageGenome-wide significant linkageFagerstrom TestCandidate gene identificationNicotine dependenceRe-sequencing studiesMeta-AnalysisSecondary analysis