Lab-on-a-chip devices as an emerging platform for stem cell biology
Gupta K, Kim DH, Ellison D, Smith C, Kundu A, Tuan J, Suh KY, Levchenko A. Lab-on-a-chip devices as an emerging platform for stem cell biology. Lab On A Chip 2010, 10: 2019-2031. PMID: 20556297, DOI: 10.1039/c004689b.Peer-Reviewed Original ResearchConceptsMicrofluidic-based approachStem cellsStem cell applicationsNovel labChip devicesChip platformHigh-throughput screeningLack of scalabilityStem cell responseLow throughputSoluble biochemical factorsHigh throughputCell applicationsRegenerative medicineStem cell biologyScalable mannerThroughputScale observationsCell microenvironmentTissue milieuPhysical cuesPlatformStem cell phenotypeMicrofabricationConventional techniques