2024
Large human cohort study of markerless head motion tracking for brain PET
Zeng T, Zhang J, Gallezot J, Fontaine K, Gravel P, Jiang W, Mulnix T, Yang Z, Zhang X, Hu L, Carson R. Large human cohort study of markerless head motion tracking for brain PET. 2024, 00: 1-2. DOI: 10.1109/nss/mic/rtsd57108.2024.10656091.Peer-Reviewed Original ResearchPost-reconstruction registrationEvent-by-eventBrain PET imagingMotion correction techniqueQuantitative PET imagingPET imagingBrain PETHead motionTime activity curvesStudy of brain functionImage qualityMotion tracking systemGray matter regionsCorrection techniqueMotionHuman cohort studiesAverage SUVPET measurementsMotion blurMatter regionsSuperior performanceTracking systemPolaris
2014
Evaluation of [18F]-(-)-norchlorofluorohomoepibatidine ([18F]-(-)-NCFHEB) as a PET radioligand to image the nicotinic acetylcholine receptors in non-human primates
Bois F, Gallezot JD, Zheng MQ, Lin SF, Esterlis I, Cosgrove KP, Carson RE, Huang Y. Evaluation of [18F]-(-)-norchlorofluorohomoepibatidine ([18F]-(-)-NCFHEB) as a PET radioligand to image the nicotinic acetylcholine receptors in non-human primates. Nuclear Medicine And Biology 2014, 42: 570-577. PMID: 25858513, PMCID: PMC4441617, DOI: 10.1016/j.nucmedbio.2014.08.003.Peer-Reviewed Original ResearchConceptsRhesus monkeysGood test-retest reproducibilityML/Plasma free fractionReceptor binding profileNicotinic acetylcholine receptorsTest-retest reproducibilityNon-human primatesReceptor radiotracerΑ4β2 receptorsFrontal cortexPET examinationsMonkey brainAcetylcholine receptorsBrain regionsDistribution volumePET radioligandMultilinear analysis methodPharmacokinetic propertiesEnd of synthesisNon-displaceable distribution volumeFree fractionPET measurementsMonkeys