Production of Octaketide Polyenes by the Calicheamicin Polyketide Synthase CalE8: Implications for the Biosynthesis of Enediyne Core Structures
Belecki K, Crawford JM, Townsend CA. Production of Octaketide Polyenes by the Calicheamicin Polyketide Synthase CalE8: Implications for the Biosynthesis of Enediyne Core Structures. Journal Of The American Chemical Society 2009, 131: 12564-12566. PMID: 19689130, PMCID: PMC2760317, DOI: 10.1021/ja904391r.Peer-Reviewed Original ResearchAntibiotics, AntineoplasticEnediynesMicromonosporaPolyenesPolyketide SynthasesProtein Structure, Tertiary