2016
Case-Control Study of Vaccine Effectiveness in Preventing Laboratory-Confirmed Influenza Hospitalizations in Older Adults, United States, 2010–2011
Havers F, Sokolow L, Shay D, Farley M, Monroe M, Meek J, Kirley P, Bennett N, Morin C, Aragon D, Thomas A, Schaffner W, Zansky S, Baumbach J, Ferdinands J, Fry A. Case-Control Study of Vaccine Effectiveness in Preventing Laboratory-Confirmed Influenza Hospitalizations in Older Adults, United States, 2010–2011. Clinical Infectious Diseases 2016, 63: 1304-1311. PMID: 27486114, DOI: 10.1093/cid/ciw512.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenza hospitalizationsCase-control studyInfluenza hospitalizationsCase patientsAge groupsRecent hospitalizationRespiratory conditionsLower functional status scoresOlder adultsConditional logistic regression modelsAdjusted VE estimatesInfluenza-associated complicationsVaccine effectiveness dataChronic medical conditionsFunctional status scoresMonths of hospitalizationChronic health conditionsLogistic regression modelsPreventing LaboratoryInfluenza vaccinationVaccination statusVaccine effectivenessInfluenza seasonVE estimatesInfluenza infection
2015
Impact of Prompt Influenza Antiviral Treatment on Extended Care Needs After Influenza Hospitalization Among Community-Dwelling Older Adults
Chaves S, Pérez A, Miller L, Bennett N, Bandyopadhyay A, Farley M, Fowler B, Hancock E, Kirley P, Lynfield R, Ryan P, Morin C, Schaffner W, Sharangpani R, Lindegren M, Tengelsen L, Thomas A, Hill M, Bradley K, Oni O, Meek J, Zansky S, Widdowson M, Finelli L. Impact of Prompt Influenza Antiviral Treatment on Extended Care Needs After Influenza Hospitalization Among Community-Dwelling Older Adults. Clinical Infectious Diseases 2015, 61: 1807-1814. PMID: 26334053, DOI: 10.1093/cid/civ733.Peer-Reviewed Original ResearchConceptsIllness onsetCommunity-dwelling adultsAntiviral treatmentExtended careCare needsEarly treatmentInfluenza hospitalizationsHospital dischargeIntensive care unit admissionLaboratory-confirmed influenza hospitalizationsOlder adultsCommunity-dwelling older adultsInfluenza antiviral treatmentPrompt antiviral treatmentCare unit admissionImpact of influenzaLength of stayRisk survival analysisUnit admissionHospital lengthInfluenza seasonShortens hospitalizationNeurologic disordersRehabilitation facilityAntiviral agentsImproving Accuracy of Influenza-Associated Hospitalization Rate Estimates - Volume 21, Number 9—September 2015 - Emerging Infectious Diseases journal - CDC
Millman A, Reed C, Kirley P, Aragon D, Meek J, Farley M, Ryan P, Collins J, Lynfield R, Baumbach J, Zansky S, Bennett N, Fowler B, Thomas A, Lindegren M, Atkinson A, Finelli L, Chaves S. Improving Accuracy of Influenza-Associated Hospitalization Rate Estimates - Volume 21, Number 9—September 2015 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2015, 21: 1595-1601. PMID: 26292017, PMCID: PMC4550134, DOI: 10.3201/eid2109.141665.Peer-Reviewed Original ResearchConceptsYears of ageHospitalization ratesAdults 18Test sensitivityLaboratory-confirmed influenza-associated hospitalizationsNational population-based surveillance systemLaboratory-confirmed influenza hospitalizationsPopulation-based surveillance systemInfectious Diseases journal - CDCInfluenza-associated hospitalizationsDiagnostic test typeFluSurv-NETInfluenza hospitalizationsInfluenza seasonPatient ageAge groupsTranscription-PCRAgeHospitalizationDiagnostic test sensitivitySensitive testAdultsSurveillance systemChildrenYearsStatin Treatment and Mortality: Propensity Score-Matched Analyses of 2007–2008 and 2009–2010 Laboratory-Confirmed Influenza Hospitalizations
Laidler M, Thomas A, Baumbach J, Kirley P, Meek J, Aragon D, Morin C, Ryan P, Schaffner W, Zansky S, Chaves S. Statin Treatment and Mortality: Propensity Score-Matched Analyses of 2007–2008 and 2009–2010 Laboratory-Confirmed Influenza Hospitalizations. Open Forum Infectious Diseases 2015, 2: ofv028. PMID: 26034777, PMCID: PMC4438907, DOI: 10.1093/ofid/ofv028.Peer-Reviewed Original ResearchPropensity score-matched analysisStatin treatmentAdjunct treatmentInfluenza virus infectionHost inflammatory responseAnnual influenza epidemicsInfluenza hospitalizationsInfluenza seasonSubstantial morbidityHospitalized cohortCox regressionImmunomodulatory agentsInflammatory responseVirus infectionProtective effectInfluenza epidemicsSurveillance dataMortalityUnmeasured confoundersStatinsDeathTreatmentVaccine productionInfluenzaPandemic
2014
600Case-control study of vaccine effectiveness in preventing influenza hospitalizations in older adults, United States, 2010-11
Havers F, Sokolow L, Farley M, Monroe M, Meek J, Kirley P, Bennett N, Morin C, Aragon D, Thomas A, Lindegren M, Zansky S, Baumbach J, Ferdinands J, Fry A. 600Case-control study of vaccine effectiveness in preventing influenza hospitalizations in older adults, United States, 2010-11. Open Forum Infectious Diseases 2014, 1: s25-s25. DOI: 10.1093/ofid/ofu051.67.Peer-Reviewed Original ResearchThe Burden of Influenza Hospitalizations in Infants From 2003 to 2012, United States
Chaves S, Perez A, Farley M, Miller L, Schaffner W, Lindegren M, Sharangpani R, Meek J, Yousey-Hindes K, Thomas A, Boulton R, Baumbach J, Hancock E, Bandyopadhyay A, Lynfield R, Morin C, Zansky S, Reingold A, Bennett N, Ryan P, Fowler B, Fry A, Finelli L. The Burden of Influenza Hospitalizations in Infants From 2003 to 2012, United States. The Pediatric Infectious Disease Journal 2014, 33: 912-919. PMID: 24577042, DOI: 10.1097/inf.0000000000000321.Peer-Reviewed Original ResearchConceptsImpact of influenzaHigh-risk conditionsHospitalization ratesRisk factorsOlder infantsIntensive care unit admissionInfluenza-associated hospitalization ratesCare unit admissionRisk conditionsInfluenza hospitalizationsUnit admissionICU admissionInfluenza vaccinationRespiratory failureClinical characteristicsInfant hospitalizationHealthy infantsMost hospitalizationsPregnant womenLung diseaseCardiovascular diseaseUS infantsHospitalizationYoung infantsInfantsChild, Household, and Caregiver Characteristics Associated with Hospitalization for Influenza Among Children 6–59 Months of Age
Dharan N, Sokolow L, Cheng P, Gargiullo P, Gershman K, Lynfield R, Morin C, Thomas A, Meek J, Farley M, Arnold K, Reingold A, Craig A, Schaffner W, Bennett N, Zansky S, Baumbach J, Lathrop S, Kamimoto L, Shay D. Child, Household, and Caregiver Characteristics Associated with Hospitalization for Influenza Among Children 6–59 Months of Age. The Pediatric Infectious Disease Journal 2014, 33: e141-e150. PMID: 24642518, PMCID: PMC4025593, DOI: 10.1097/inf.0000000000000283.Peer-Reviewed Original ResearchConceptsMonths of ageChildren 6Influenza hospitalizationsInfluenza illnessInfluenza vaccinationMaternal ageRisk factorsSevere outcomesChronic illnessEmerging Infections Program sitesLaboratory-confirmed influenza infectionIndependent risk factorInfluenza-associated hospitalizationsYoung maternal ageCase-control studyConditional logistic regressionYoung childrenHematologic/Influenza immunizationHousehold smokingEligible casesInfluenza infectionNeurologic conditionsEligible controlsMedical records
2013
Complications and Associated Bacterial Coinfections Among Children Hospitalized With Seasonal or Pandemic Influenza, United States, 2003–2010
Dawood F, Chaves S, Pérez A, Reingold A, Meek J, Farley M, Ryan P, Lynfield R, Morin C, Baumbach J, Bennett N, Zansky S, Thomas A, Lindegren M, Schaffner W, Finelli L, Network F. Complications and Associated Bacterial Coinfections Among Children Hospitalized With Seasonal or Pandemic Influenza, United States, 2003–2010. The Journal Of Infectious Diseases 2013, 209: 686-694. PMID: 23986545, DOI: 10.1093/infdis/jit473.Peer-Reviewed Original ResearchConceptsIntensive carePandemic influenzaLaboratory-confirmed influenza hospitalizationsBacteremia/sepsisInfluenza-associated complicationsIntensive care requirementAcute renal failurePopulation-based surveillanceSeverity of complicationsMedian hospitalization durationNinth Revision codesInfluenza hospitalizationsAsthma exacerbationsHospitalization durationInfluenza vaccinationRespiratory failureCommon complicationRenal failureBacterial coinfectionProlonged hospitalizationMedian lengthPrimary preventionRevision codesSeasonal influenzaHospitalized childrenEffectiveness of Nonadjuvanted Monovalent Influenza A(H1N1)pdm09 Vaccines for Preventing Reverse Transcription Polymerase Chain Reaction–Confirmed Pandemic Influenza Hospitalizations: Case-Control Study of Children and Adults at 10 US Influenza Surveillance Network Sites
Thompson M, Sokolow L, Almendares O, Openo K, Farley M, Meek J, Ray J, Kirley P, Reingold A, Aragon D, Hancock E, Baumbach J, Schaffner W, Thomas A, Lynfield R, Ryan P, Monroe M, Cheng P, Fry A, Shay D. Effectiveness of Nonadjuvanted Monovalent Influenza A(H1N1)pdm09 Vaccines for Preventing Reverse Transcription Polymerase Chain Reaction–Confirmed Pandemic Influenza Hospitalizations: Case-Control Study of Children and Adults at 10 US Influenza Surveillance Network Sites. Clinical Infectious Diseases 2013, 57: 1587-1592. PMID: 23956169, PMCID: PMC7314184, DOI: 10.1093/cid/cit551.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed pandemic influenzaCommunity-matched controlsCase-control studyReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionInfluenza hospitalizationsMonovalent influenzaPandemic influenzaSingle dosePolymerase chain reactionVirus infectionInfluenzaChain reactionHospitalizationVaccinePatientsInfectionDose
2010
Burden of Seasonal Influenza Hospitalization in Children, United States, 2003 to 2008
Dawood FS, Fiore A, Kamimoto L, Bramley A, Reingold A, Gershman K, Meek J, Hadler J, Arnold KE, Ryan P, Lynfield R, Morin C, Mueller M, Baumbach J, Zansky S, Bennett NM, Thomas A, Schaffner W, Kirschke D, Finelli L, Network E. Burden of Seasonal Influenza Hospitalization in Children, United States, 2003 to 2008. The Journal Of Pediatrics 2010, 157: 808-814. PMID: 20580018, DOI: 10.1016/j.jpeds.2010.05.012.Peer-Reviewed Original ResearchConceptsSevere outcomesInfluenza hospitalizationsHospitalization ratesHospitalized childrenEmerging Infections Program NetworkIntensive care unit admissionInfections Program NetworkSeasonal influenza hospitalizationsCare unit admissionLaboratory-confirmed influenzaPopulation-based surveillanceUnderlying medical conditionsHigher hospitalization ratesRate of hospitalizationProportion of childrenRapid diagnostic testsUnit admissionRespiratory failureBacterial coinfectionClinical courseHospital recordsSeasonal influenzaMedical historyDisease burdenIncidence rate