2022
Early Release - Economic Burden of Reported Lyme Disease in High-Incidence Areas, United States, 2014–2016 - Volume 28, Number 6—June 2022 - Emerging Infectious Diseases journal - CDC
Hook S, Jeon S, Niesobecki S, Hansen A, Meek J, Bjork J, Dorr F, Rutz H, Feldman K, White J, Backenson P, Shankar M, Meltzer M, Hinckley A. Early Release - Economic Burden of Reported Lyme Disease in High-Incidence Areas, United States, 2014–2016 - Volume 28, Number 6—June 2022 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2022, 28: 1170-1179. PMID: 35608612, PMCID: PMC9155891, DOI: 10.3201/eid2806.211335.Peer-Reviewed Original ResearchConceptsTotal societal costsSocietal costsLyme diseasePatient costsInfectious Diseases journal - CDCMean patient costMean societal costLyme disease endemic stateTotal patient costsCost-effectiveness analysisDisseminated diseaseProspective studyEarly diagnosisIncidence areaDiseaseEffective preventionProbable diseaseDemographic factorsPrevention methodsComprehensive economic evaluationEconomic evaluationPatientsVaccineIllnessDiagnosis
2021
Prevention of Lyme and other tickborne diseases using a rodent‐targeted approach: A randomized controlled trial in Connecticut
Hinckley A, Niesobecki S, Connally N, Hook S, Biggerstaff B, Horiuchi K, Hojgaard A, Mead P, Meek J. Prevention of Lyme and other tickborne diseases using a rodent‐targeted approach: A randomized controlled trial in Connecticut. Zoonoses And Public Health 2021, 68: 578-587. PMID: 34050628, PMCID: PMC10898493, DOI: 10.1111/zph.12844.Peer-Reviewed Original ResearchConceptsTickborne diseasesTreatment groupsInfection ratePlacebo-controlled trialPublic health problemTick encountersIxodes scapularis ticksTick exposureHousehold membersHealth problemsPathogen infection ratesDiseaseScapularis ticksSignificant differencesNymphal ticksTransmission cycleTrialsEnzootic cycleInterventionPathogen transmission cyclesBait boxesBiannual surveysGroupTicksYears
2017
Pet ownership increases human risk of encountering ticks
Jones E, Hinckley A, Hook S, Meek J, Backenson B, Kugeler K, Feldman K. Pet ownership increases human risk of encountering ticks. Zoonoses And Public Health 2017, 65: 74-79. PMID: 28631423, PMCID: PMC7053298, DOI: 10.1111/zph.12369.Peer-Reviewed Original Research
2016
Effectiveness of Residential Acaricides to Prevent Lyme and Other Tick-borne Diseases in Humans
Hinckley A, Meek J, Ray J, Niesobecki S, Connally N, Feldman K, Jones E, Backenson P, White J, Lukacik G, Kay A, Miranda W, Mead P. Effectiveness of Residential Acaricides to Prevent Lyme and Other Tick-borne Diseases in Humans. The Journal Of Infectious Diseases 2016, 214: 182-188. PMID: 26740276, PMCID: PMC10874626, DOI: 10.1093/infdis/jiv775.Peer-Reviewed Original ResearchConceptsTick-borne diseasesHuman-tick encountersMajor public health concernPlacebo-controlled trialMedical record reviewHuman tick-borne diseasesReports of illnessPublic health concernPublic health authoritiesTick-borne diseaseRecord reviewTick biteTick exposureTreatment groupsHealth authoritiesDiseaseHealth concernQuesting ticksHuman outcomesTicksUse of acaricidesIllnessIncidenceTrialsWeeks
2015
Testing practices and volume of non-Lyme tickborne diseases in the United States
Connally N, Hinckley A, Feldman K, Kemperman M, Neitzel D, Wee S, White J, Mead P, Meek J. Testing practices and volume of non-Lyme tickborne diseases in the United States. Ticks And Tick-borne Diseases 2015, 7: 193-198. PMID: 26565931, PMCID: PMC4659751, DOI: 10.1016/j.ttbdis.2015.10.005.Peer-Reviewed Original Research
2009
Peridomestic Lyme Disease Prevention Results of a Population-Based Case–Control Study
Connally NP, Durante AJ, Yousey-Hindes KM, Meek JI, Nelson RS, Heimer R. Peridomestic Lyme Disease Prevention Results of a Population-Based Case–Control Study. American Journal Of Preventive Medicine 2009, 37: 201-206. PMID: 19595558, DOI: 10.1016/j.amepre.2009.04.026.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnimalsCase-Control StudiesChildChild, PreschoolConnecticutEnvironment DesignEnvironmental ExposureFemaleHumansHygieneInfantLogistic ModelsLyme DiseaseMaleMatched-Pair AnalysisMiddle AgedPopulation SurveillanceProspective StudiesResidence CharacteristicsRisk FactorsSurveys and QuestionnairesTicksYoung AdultConceptsCase-control studyLyme diseaseDisease prevention initiativesConditional logistic regressionDisease prevention measuresErythema migransPotential confoundersRecreational exposureLogistic regressionProspective ageDiseaseCase onsetPrevention resultsPrevention measuresPersonal protectionRiskHoursConfoundersMigransTicksInfectionStudyConnecticut communitiesMonths
2008
The mortality burden of chronic liver disease may be substantially underestimated in the United States.
Durante AJ, St Louis T, Meek JI, Navarro VJ, Sofair AN. The mortality burden of chronic liver disease may be substantially underestimated in the United States. Connecticut Medicine 2008, 72: 389-92. PMID: 18763665.Peer-Reviewed Original ResearchConceptsChronic liver diseaseICD-10 codesLiver diseaseEnd-stage liver diseaseStage liver diseaseDeath certificate dataCause of deathMedical examiner recordsCLD burdenCLD statusMedical chartsMortality burdenDeath certificatesCertificate dataHealth StatisticsCounty residentsDiseaseGold standardBurdenSerious diseaseDeathUnited States National CenterDetrimental effectsSpecificityPreventionPerformance of an Algorithm for Assessing Smallpox Risk among Patients with Rashes That May Be Confused with Smallpox
Hutchins S, Sulemana I, Heilpern K, Schaffner W, Wax G, Lerner E, Watson B, Baltimore R, Waltenburg R, Aronsky D, Coffin S, Ng G, Craig A, Behrman A, Meek J, Sherman E, Chavez S, Harpaz R, Schmid S. Performance of an Algorithm for Assessing Smallpox Risk among Patients with Rashes That May Be Confused with Smallpox. Clinical Infectious Diseases 2008, 46: s195-s203. PMID: 18284359, DOI: 10.1086/524383.Peer-Reviewed Original Research
2002
Spatial Analysis of Human Granulocytic Ehrlichiosis near Lyme, Connecticut - Volume 8, Number 9—September 2002 - Emerging Infectious Diseases journal - CDC
Chaput EK, Meek JI, Heimer R. Spatial Analysis of Human Granulocytic Ehrlichiosis near Lyme, Connecticut - Volume 8, Number 9—September 2002 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2002, 8: 943-948. PMID: 12194771, PMCID: PMC2732548, DOI: 10.3201/eid0809.020103.Peer-Reviewed Original ResearchSuperoxide Anion Production during Anaplasma phagocytophila Infection
Wang T, Malawista SE, Pal U, Grey M, Meek J, Akkoyunlu M, Thomas V, Fikrig E. Superoxide Anion Production during Anaplasma phagocytophila Infection. The Journal Of Infectious Diseases 2002, 186: 274-280. PMID: 12134266, DOI: 10.1086/341451.Peer-Reviewed Original ResearchConceptsChronic granulomatous diseaseRespiratory burstA. phagocytophilaRespiratory burst inhibitionNitroblue tetrazoliumPopulation of neutrophilsSuperoxide anion productionInfected miceGranulomatous diseaseMouse modelUse of assaysPolymorphonuclear leukocytesUninfected animalsAnaplasma phagocytophilaAnion productionNeutrophilsInfectionHL-60 cellsIndividual cell basisAssaysCell basisCellsPatientsLeukocytesDisease
2000
The Emergence of Another Tickborne Infection in the 12-Town Area around Lyme, Connecticut: Human Granulocytic Ehrlichiosis
IJdo J, Meek J, Cartter M, Magnarelli L, Wu C, Tenuta S, Fikrig E, Ryder R. The Emergence of Another Tickborne Infection in the 12-Town Area around Lyme, Connecticut: Human Granulocytic Ehrlichiosis. The Journal Of Infectious Diseases 2000, 181: 1388-1393. PMID: 10751139, DOI: 10.1086/315389.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisTickborne infectionProspective population-based surveillanceGranulocytic ehrlichiosisCommon tickborne infectionPopulation-based surveillancePrimary care providersSubset of seraIndirect fluorescent antibody methodIllness suggestiveCare providersLaboratory evidenceImportant causeProbable casesFluorescent antibody methodImmunoblot assayLyme diseaseInfectionAntibody methodIncidenceEhrlichiosisLymeMorbidityDiseaseSuggestive
1996
Underreporting of Lyme Disease by Connecticut Physicians, 1992
Meek J, Roberts C, Smith E, Cartter M. Underreporting of Lyme Disease by Connecticut Physicians, 1992. Journal Of Public Health Management And Practice 1996, 2: 61-65. PMID: 10186700, DOI: 10.1097/00124784-199623000-00017.Peer-Reviewed Original Research