2015
The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576)
Weisman O, Pelphrey KA, Leckman JF, Feldman R, Lu Y, Chong A, Chen Y, Monakhov M, Chew SH, Ebstein RP. The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576). Psychoneuroendocrinology 2015, 58: 23-32. PMID: 25935637, DOI: 10.1016/j.psyneuen.2015.04.007.Peer-Reviewed Original ResearchConceptsOxytocin receptor geneCognitive empathyRMET performanceFetal testosteroneHuman social cognitionSocial-cognitive developmentSocio-cognitive skillsRole of oxytocinSocio-affective skillsSocial cognitionPsychosocial competenceHigh fetal testosteroneIndividual differencesCognitive developmentBaron-CohenEmotional statesOXTR rs53576OXTR geneGreater identificationEmpathyCore aspectsRMETCognitionUnique supportTestosterone system
2002
Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome
Zhang H, Leckman JF, Pauls DL, Tsai CP, Kidd KK, Campos MR, Genetics T. Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome. American Journal Of Human Genetics 2002, 70: 896-904. PMID: 11840360, PMCID: PMC379118, DOI: 10.1086/339520.Peer-Reviewed Original ResearchAllelesBehavioral SymptomsChromosomes, HumanChromosomes, Human, Pair 17Chromosomes, Human, Pair 4Chromosomes, Human, Pair 5Gene FrequencyGenetic LinkageGenetic MarkersGenome, HumanHumansMatched-Pair AnalysisNuclear FamilyObsessive-Compulsive DisorderPhenotypeQuantitative Trait, HeritableSoftwareStatistics, NonparametricTourette Syndrome
1996
Linkage disequilibrium between an allele at the dopamine D4 receptor locus and Tourette syndrome, by the transmission-disequilibrium test.
Grice DE, Leckman JF, Pauls DL, Kurlan R, Kidd KK, Pakstis AJ, Chang FM, Buxbaum JD, Cohen DJ, Gelernter J. Linkage disequilibrium between an allele at the dopamine D4 receptor locus and Tourette syndrome, by the transmission-disequilibrium test. American Journal Of Human Genetics 1996, 59: 644-52. PMID: 8751866, PMCID: PMC1914894.Peer-Reviewed Original ResearchConceptsTourette syndromeChronic multiple ticsMultiple ticsTransmission disequilibrium test (TDT) methodsDopaminergic abnormalitiesFamily triosTransmission disequilibrium testReceptor locusSyndromeDopamine D4 receptor locusFunctional mutationsFunctional studiesCommon allelesAllelesPathogenesisParticular allelesDifferent binding propertiesAbnormalities
1994
D2 Dopamine Receptor Alleles Do Not Influence Severity of Tourette's Syndrome: Results From Four Large Kindreds
Gelernter J, Pauls DL, Leckman J, Kidd KK, Kurlan R. D2 Dopamine Receptor Alleles Do Not Influence Severity of Tourette's Syndrome: Results From Four Large Kindreds. JAMA Neurology 1994, 51: 397-400. PMID: 8155017, DOI: 10.1001/archneur.1994.00540160099012.Peer-Reviewed Original Research