2018
Aggressive infrainguinal revascularization in renal transplant patients is justifiable
Craig-Schapiro R, Nejim B, Arhuidese I, Malas M. Aggressive infrainguinal revascularization in renal transplant patients is justifiable. American Journal Of Transplantation 2018, 18: 1718-1725. PMID: 29288558, DOI: 10.1111/ajt.14636.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalFemaleFollow-Up StudiesHumansKidney Failure, ChronicKidney TransplantationLimb SalvageLower ExtremityMaleMiddle AgedPatient SelectionPostoperative ComplicationsPrognosisReoperationRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateTime FactorsVascular GraftingVascular PatencyConceptsCritical limb ischemiaRenal transplant patientsTransplant patientsNontransplant patientsLimb ischemiaPrimary patencyInfrainguinal revascularizationRisk factorsMultivariate Cox regression analysisVascular Quality Initiative databaseEnd-stage renal diseaseDistal bypassCox regression analysisOutcomes of lower extremity revascularizationPrimary patency lossLower extremity revascularizationAmputation-free survivalLimb salvage outcomesAssociated with limb lossOverall survivalProsthetic conduitVein conduitPatency lossRenal diseaseInfrainguinal bypass
2017
Outcomes of Primary and Secondary Carotid Artery Stenting
Arhuidese I, Rizwan M, Nejim B, Malas M. Outcomes of Primary and Secondary Carotid Artery Stenting. Stroke 2017, 48: 3086-3092. PMID: 28974632, DOI: 10.1161/strokeaha.117.016963.Peer-Reviewed Original ResearchConceptsAssociated with significantly lower oddsSymptomatic patientsSignificantly lower oddsLower oddsIpsilateral carotid endarterectomyCox regression analysisOdds of hypotensionCarotid artery stentingVascular Quality InitiativeAsymptomatic patientsOdds of hypertensionKaplan-MeierPeriprocedural stroke/deathCAS proceduresPeriprocedural hypotensionArtery stentingCarotid angioplastyCarotid endarterectomyPatientsStroke/deathEvaluate outcomesOddsHypotensionBradycardiaStent
2016
Perioperative and Long-term Outcomes After Carotid Endarterectomy in Hemodialysis Patients
Cooper M, Arhuidese I, Obeid T, Hicks C, Canner J, Malas M. Perioperative and Long-term Outcomes After Carotid Endarterectomy in Hemodialysis Patients. JAMA Surgery 2016, 151: 947-952. PMID: 27366897, DOI: 10.1001/jamasurg.2016.1504.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAsymptomatic DiseasesDatabases, FactualEndarterectomy, CarotidFemaleHeart FailureHispanic or LatinoHumansKidney Failure, ChronicMaleMiddle AgedMobility LimitationMyocardial InfarctionPostoperative PeriodPulmonary Disease, Chronic ObstructiveRenal DialysisRetrospective StudiesRisk FactorsSex FactorsSmokingStrokeSurvival RateTime FactorsUnited StatesConceptsLong-term outcomesRisk of carotid endarterectomyAsymptomatic patientsLong-term strokeSymptomatic patientsCarotid endarterectomyDialysis patientsPerioperative strokeCohort of symptomatic patientsHistory of congestive heart failureMedian follow-up timePredictor of long-term mortalityMyocardial infarctionAssociated with poor outcomesDialysis-dependent patientsFollow-up timeOutcomes of carotid endarterectomyCox regression analysisCongestive heart failurePredictors of perioperative strokeLong-term mortalityChronic obstructive pulmonary diseaseDecrease stroke riskObstructive pulmonary diseasePatient-important
2015
Vascular access modifies the protective effect of obesity on survival in hemodialysis patients
Arhuidese I, Obeid T, Hicks C, Qazi U, Botchey I, Zarkowsky D, Reifsnyder T, Malas M. Vascular access modifies the protective effect of obesity on survival in hemodialysis patients. Surgery 2015, 158: 1628-1634. PMID: 26126794, DOI: 10.1016/j.surg.2015.04.036.Peer-Reviewed Original ResearchConceptsBody mass indexEnd-stage renal diseaseNormal body mass indexProtective effect of obesityHigher body mass indexEffect of obesityObesity paradoxProtective effect of increasing BMIEffect of increased BMIBody mass index statusMass indexHD accessProtective effectAssociated with lower mortalityPropensity score matching analysisSurvival of patientsScore matching analysisSurvival benefitImproved survivalRetrospective studyHemodialysis accessInitiate hemodialysisPatient backgroundRenal diseaseCox regressionTrends in Incident Hemodialysis Access and Mortality
Malas MB, Canner JK, Hicks CW, Arhuidese IJ, Zarkowsky DS, Qazi U, Schneider EB, Black JH, Segev DL, Freischlag JA. Trends in Incident Hemodialysis Access and Mortality. JAMA Surgery 2015, 150: 441-448. PMID: 25738981, DOI: 10.1001/jamasurg.2014.3484.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseHemodialysis cathetersArteriovenous fistulaArteriovenous graftsLower mortalityRenal diseaseVascular accessHD outcomesNational Kidney Foundation Kidney Disease Outcomes Quality InitiativeKidney Foundation Kidney Disease Outcomes Quality InitiativeMultivariable Cox proportional hazards modelsPrior renal replacement therapyUS Renal Data SystemCox proportional hazards modelArteriovenous fistula useIncident HD patientsInitiation of hemodialysisRetrospective cohort studyRenal replacement therapyProportional hazards modelFistula useCohort studySurvival benefitHD patientsPropensity score-matching technique
2014
Design of the Revascularization With Open Bypass vs Angioplasty and Stenting of the Lower Extremity Trial (ROBUST): A Randomized Clinical Trial
Malas M, Qazi U, Glebova N, Arhuidese I, Reifsnyder T, Black J, Perler B, Freischlag J. Design of the Revascularization With Open Bypass vs Angioplasty and Stenting of the Lower Extremity Trial (ROBUST): A Randomized Clinical Trial. JAMA Surgery 2014, 149: 1289-1295. PMID: 25353642, DOI: 10.1001/jamasurg.2014.369.Peer-Reviewed Original ResearchConceptsReduce health care costsRandomized clinical trialsOpen bypassPercutaneous transluminal angioplastyCritical limb ischemiaHospital admission costsQuality-of-life questionnaireHealth care costsAnkle brachial indexQuality of lifeImprovement of quality of lifeEXTREME trialClinical trialsTransluminal angioplastyLimb ischemiaAmputation-free survivalTransAtlantic Inter-Society ConsensusCare costsRobust trialsFemoropopliteal bypassTASC II BSecondary aimAdmission costsBrachial indexSuperficial femoral artery lesionsPerioperative Mortality Following Repair of Abdominal Aortic Aneurysms: Application of a Randomized Clinical Trial to Real-World Practice Using a Validated Nationwide Data Set
Malas M, Arhuidese I, Qazi U, Black J, Perler B, Freischlag J. Perioperative Mortality Following Repair of Abdominal Aortic Aneurysms: Application of a Randomized Clinical Trial to Real-World Practice Using a Validated Nationwide Data Set. JAMA Surgery 2014, 149: 1260-1265. PMID: 25337871, DOI: 10.1001/jamasurg.2014.275.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramEndovascular aneurysm repairAbdominal aortic aneurysmInfrarenal abdominal aortic aneurysmRandomized clinical trialsPerioperative mortalityOpen repairClinical trialsAortic aneurysmAsymptomatic infrarenal abdominal aortic aneurysmVeterans Affairs Cooperative trialNational Surgical Quality Improvement Program cohortAmerican College of Surgeons National Surgical Quality Improvement ProgramSurgeons National Surgical Quality Improvement ProgramNSQIP databaseElective endovascular aneurysm repairRepair of abdominal aortic aneurysmsSurgical Quality Improvement ProgramCompare 30-day mortalityThirty-day mortalityHigh-risk patientsQuality Improvement ProgramProportion of patientsDay of surgeryIndividualized assessment of risk