2024
Generalizable and replicable brain-based predictions of cognitive functioning across common psychiatric illness
Chopra S, Dhamala E, Lawhead C, Ricard J, Orchard E, An L, Chen P, Wulan N, Kumar P, Rubenstein A, Moses J, Chen L, Levi P, Holmes A, Aquino K, Fornito A, Harpaz-Rotem I, Germine L, Baker J, Yeo B, Holmes A. Generalizable and replicable brain-based predictions of cognitive functioning across common psychiatric illness. Science Advances 2024, 10: eadn1862. PMID: 39504381, PMCID: PMC11540040, DOI: 10.1126/sciadv.adn1862.Peer-Reviewed Original ResearchConceptsPrediction of cognitionCognitive functionPrediction of cognitive functionFunctional neuroimaging dataTransdiagnostic sampleComputational psychiatryPsychiatric illnessNeuroimaging dataCognitive impairmentCognitionPopulation-level datasetsPsychiatryAssociated with poor outcomesUK BiobankImpairmentBrainIllnessSymptomsPrediction studiesParticipantsPoor outcomeClinical studiesSamples
2019
Endocannabinoid System Alterations in Posttraumatic Stress Disorder: A Review of Developmental and Accumulative Effects of Trauma
Nia A, Bender R, Harpaz-Rotem I. Endocannabinoid System Alterations in Posttraumatic Stress Disorder: A Review of Developmental and Accumulative Effects of Trauma. Chronic Stress 2019, 3: 2470547019864096. PMID: 31660473, PMCID: PMC6816276, DOI: 10.1177/2470547019864096.Peer-Reviewed Original ResearchEndocannabinoid system alterationsEndocannabinoid systemSystem alterationsEndocannabinoid ligandsProlonged stressPosttraumatic stress disorderImportant sex differencesClinical studiesPsychiatric symptomsCannabinoid receptorsHuman studiesChronic stressStress disorderTraumaDecreased levelsDevelopmental ageSex differencesCurrent literatureReceptorsAlterationsAccumulative effectReviewSymptomsLevels