2017
Beta‐blockers in hospitalised patients with cirrhosis and ascites: mortality and factors determining discontinuation and reinitiation
Bhutta A, Garcia‐Tsao G, Reddy K, Tandon P, Wong F, O'Leary J, Acharya C, Banerjee D, Abraldes J, Jones T, Shaw J, Deng Y, Ciarleglio M, Bajaj J. Beta‐blockers in hospitalised patients with cirrhosis and ascites: mortality and factors determining discontinuation and reinitiation. Alimentary Pharmacology & Therapeutics 2017, 47: 78-85. PMID: 28994122, PMCID: PMC6016372, DOI: 10.1111/apt.14366.Peer-Reviewed Original ResearchConceptsMean arterial pressureBeta-blocker useLower mean arterial pressureBeta-blocker discontinuationRefractory ascitesHigh mortalityLower white blood cell countBeneficial anti-inflammatory effectsWhite blood cell countAcute kidney injuryAnti-inflammatory effectsTime of discontinuationBlood cell countEffect of BBBB discontinuationKidney injuryChart reviewHospital dischargeArterial pressureDiscontinuationAscitesCirrhosisPatientsCell countMortality
2012
Paracentesis
De Gottardi A, Yeo C, Garcia‐Tsao G. Paracentesis. 2012, 1158-1162. DOI: 10.1002/9781118321386.ch154.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsDiagnostic paracentesisTherapeutic paracentesisAscitic fluidNew-onset ascitesAdministration of albuminSpontaneous bacterial peritonitisSite of paracentesisFormal contraindicationBowel perforationAbdominal ultrasoundBacterial peritonitisMajor complicationsSpecific etiologyAbdominal cavityParacentesisAscitesCell countBlood culture bottlesPatient consentSingle procedureFrequent technical problemsLeakage of fluidTherapeutic purposesPatientsMedical proceduresAscites
Garcia‐Tsao G. Ascites. 2012, 103-106. DOI: 10.1002/9781118321386.ch17.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsRight heart failurePeritoneal malignancyHeart failureHepatic sinusoidal pressureLow-protein ascitesNew-onset ascitesSpontaneous bacterial peritonitisEtiology of ascitesRoutine laboratory testsRisk of infectionAccumulation of fluidDiagnostic paracentesisBacterial peritonitisCareful historyPhysical examinationCirrhotic ascitesLiver architecturePeritoneal cavityHepatic sinusoidsAscitesPeritoneal lymphaticsCell countCirrhosisProtein levelsSinusoidal pressure
2009
Incidence, Prevalence, and Clinical Significance of Abnormal Hematologic Indices in Compensated Cirrhosis
Qamar AA, Grace ND, Groszmann RJ, Garcia–Tsao G, Bosch J, Burroughs AK, Ripoll C, Maurer R, Planas R, Escorsell A, Garcia–Pagan J, Patch D, Matloff DS, Makuch R, Rendon G, Group P. Incidence, Prevalence, and Clinical Significance of Abnormal Hematologic Indices in Compensated Cirrhosis. Clinical Gastroenterology And Hepatology 2009, 7: 689-695. PMID: 19281860, PMCID: PMC4545534, DOI: 10.1016/j.cgh.2009.02.021.Peer-Reviewed Original ResearchConceptsHepatic venous pressure gradientHematologic indicesCompensated cirrhosisBaseline hepatic venous pressure gradientWhite blood cell countChild-Pugh scorePredictors of deathPrimary end pointVenous pressure gradientDevelopment of varicesKaplan-Meier analysisBlood cell countCombination of leukopeniaBaseline thrombocytopeniaVariceal bleedingClinical decompensationEsophageal varicesPrognostic significanceTransplant surgeryClinical significanceLeukopeniaThrombocytopeniaCirrhosisCell countVarices
1985
The diagnosis of bacterial peritonitis: Comparison of pH, lactate concentration and leukocyte count
Garcia‐Tsao G, Conn H, Lerner E. The diagnosis of bacterial peritonitis: Comparison of pH, lactate concentration and leukocyte count. Hepatology 1985, 5: 91-96. PMID: 3967868, DOI: 10.1002/hep.1840050119.Peer-Reviewed Original ResearchConceptsPolymorphonuclear cell countAscitic fluid lactateBacterial peritonitisAscitic fluidPeritoneal metastasisAscitic fluid polymorphonuclear cell countLactate gradientLactate concentrationAscitic fluid glucoseDiagnostic cutoff levelUninfected ascitesCirrhotic patientsLiver involvementTuberculous peritonitisConsecutive patientsPMN countArterial lactateLeukocyte countArterial bloodCutoff levelCell countFluid glucosePeritonitisPatientsDiagnostic accuracy