2022
Brain-behavior relationships of simulated naturalistic automobile driving under the influence of acute cannabis intoxication: A double-blind, placebo-controlled study
Meda S, Stevens M, Boer E, Boyle C, Book G, Ward N, Pearlson G. Brain-behavior relationships of simulated naturalistic automobile driving under the influence of acute cannabis intoxication: A double-blind, placebo-controlled study. 2022 DOI: 10.26828/cannabis.2022.02.000.32.Peer-Reviewed Original ResearchBrain-behavior relationshipsEffects of cannabisFunctional MRICar followingMotion-sensitive visual cortexSpecific driving skillsInferior frontal gyrusSuperior temporal gyrusFrequent cannabis usersComplex everyday activitiesGroup independent component analysisInfluence of cannabisAcute cannabis intoxicationBehavioral factorsKey brain areasIndependent component analysisFrontal gyrusDriving skillsBehavior factorsTemporal gyrusDifferent driving behaviorsSafe overtakingCannabis usersConnectivity differencesFMRI data
2013
Resting State Electroencephalogram Oscillatory Abnormalities in Schizophrenia and Psychotic Bipolar Patients and Their Relatives from the Bipolar and Schizophrenia Network on Intermediate Phenotypes Study
Narayanan B, O’Neil K, Berwise C, Stevens MC, Calhoun VD, Clementz BA, Tamminga CA, Sweeney JA, Keshavan MS, Pearlson GD. Resting State Electroencephalogram Oscillatory Abnormalities in Schizophrenia and Psychotic Bipolar Patients and Their Relatives from the Bipolar and Schizophrenia Network on Intermediate Phenotypes Study. Biological Psychiatry 2013, 76: 456-465. PMID: 24439302, PMCID: PMC5045030, DOI: 10.1016/j.biopsych.2013.12.008.Peer-Reviewed Original ResearchConceptsFirst-degree relativesSlow beta activityFast alpha activitySZ probandsAlpha activityHealthy control subjectsBeta activityRelative risk estimatesFrontal delta activityEEG spectral activityModerate relative riskPsychotic bipolar patientsLow-frequency activityPsychotic bipolar probandsGroup independent component analysisControl subjectsRelative riskPost-hoc pair-wise comparisonsBipolar patientsGenetic predispositionIntermediate Phenotypes (B-SNIP) studyOscillatory abnormalitiesAnalysis of covarianceUnique endophenotypesBipolar disorder