2002
Acute pancreatitis
Nagar AB, Gorelick FS. Acute pancreatitis. Current Opinion In Gastroenterology 2002, 18: 552-557. PMID: 17033332, DOI: 10.1097/00001574-200209000-00005.Peer-Reviewed Original ResearchSystemic inflammatory responseAcute pancreatitisInflammatory responseDistant organ failureMultiple inciting factorsEndoscopic retrograde cholangiopancreatography (ERCP) resultsSpecific inflammatory mediatorsAcute pancreatic injuryHuman acute pancreatitisExperimental acute pancreatitisIntra-acinar activationRelease of cytokinesClinical acute pancreatitisMultiorgan failurePancreatic injuryOrgan failureProinflammatory mediatorsInflammatory mediatorsCascade of eventsClinical syndromePancreatitisAnimal modelsInciting factorsMajor determinantMediators
1999
ETIOPATHOGENESIS OF ACUTE PANCREATITIS
Karne S, Gorelick F. ETIOPATHOGENESIS OF ACUTE PANCREATITIS. Surgical Clinics Of North America 1999, 79: 699-710. PMID: 10470320, DOI: 10.1016/s0039-6109(05)70036-0.Peer-Reviewed Original ResearchConceptsAcute pancreatitisCourse of APPotent proteolytic enzymesCapillary leak syndromeAcinar cellsPreliminary clinical studySpecific clinical settingsSystemic complicationsLeak syndromeCytokine inhibitorsInflammatory moleculesCascade of eventsInflammatory cellsPancreatic edemaVasoactive moleculesClinical studiesParticular neutrophilsPancreatitisFurther secretionClinical settingNitric oxideComplement systemCytokinesPremature activationImmediate release