From Connectivity to Controllability: Unraveling the Brain Biomarkers of Major Depressive Disorder
Pan C, Ma Y, Wang L, Zhang Y, Wang F, Zhang X. From Connectivity to Controllability: Unraveling the Brain Biomarkers of Major Depressive Disorder. Brain Sciences 2024, 14: 509. PMID: 38790487, PMCID: PMC11119370, DOI: 10.3390/brainsci14050509.Peer-Reviewed Original ResearchMajor depressive disorderFunctional magnetic resonance imagingDepressive disorderTreatment of Major Depressive DisorderBiomarkers of major depressive disorderBrain functional networksDevelopment of precision medicine strategiesBrain regionsNetwork topology perspectiveNetwork neuroscienceBrain biomarkersBrain's abilityBrain statesPersonalized interventionsFunctional networksBrainMagnetic resonance imagingEfficacy of treatmentDisordersResonance imagingTopological perspectivePathological profileComplex dynamicsNeuroscienceLearningA role for the cerebellum in motor-triggered alleviation of anxiety
Zhang X, Wu W, Shen L, Ji M, Zhao P, Yu L, Yin J, Xie S, Xie Y, Zhang Y, Li H, Zhang Q, Yan C, Wang F, De Zeeuw C, Wang J, Zhu J. A role for the cerebellum in motor-triggered alleviation of anxiety. Neuron 2024, 112: 1165-1181.e8. PMID: 38301648, DOI: 10.1016/j.neuron.2024.01.007.Peer-Reviewed Original ResearchAlleviation of anxietyAnxiolytic effectsDentate neuronsBrain mechanismsOrexinergic projectionsAmygdalar neuronsEmotional systemsCerebellar dentate nucleusAnxietyReduce anxietyPhysical exerciseMotor systemRotarodHypothalamic neuronsDentate nucleusNeuronsAmygdalaSubject animalsDentateCerebellumBrainAnimals