Potential for Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy for Lung Cancer with 4-Dimensional Robust Optimization
Ge S, Wang X, Liao Z, Zhang L, Sahoo N, Yang J, Guan F, Mohan R. Potential for Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy for Lung Cancer with 4-Dimensional Robust Optimization. Cancers 2019, 11: 35. PMID: 30609652, PMCID: PMC6356681, DOI: 10.3390/cancers11010035.Peer-Reviewed Original ResearchLung cancer patientsIntensity-modulated proton therapyCancer patientsIMPT dose distributionsClinical target volume coverageNormal tissue dose distributionsTarget volume coveragePlanning target volumeTarget dose coverageConventional planning target volumeRespiratory motionDose distributionDifferent tumor sizesTarget dose distributionProton therapyTumor sizeLung cancerDose coverageTreatment planIMPT plansTarget volumeNormal tissuesVolume coverageRespiratory phasesPatients