2025
HER2DX in HER2-positive inflammatory breast cancer: correlative insights and comparative analysis with noninflammatory breast cancers ☆
Lynce F, Martínez-Sáez O, Walbaum B, Brasó-Maristany F, Waks A, Villagrasa P, Javierre G, Sanfeliu E, Galván P, Paré L, Anderson L, Perou C, Parker J, Vivancos A, DiLullo M, Pernas S, Winer E, Overmoyer B, Mittendorf E, Bueno-Muiño C, Martín M, Prat A, Tolaney S. HER2DX in HER2-positive inflammatory breast cancer: correlative insights and comparative analysis with noninflammatory breast cancers ☆. ESMO Open 2025, 10: 104100. PMID: 39826476, DOI: 10.1016/j.esmoop.2024.104100.Peer-Reviewed Original ResearchHER2-positive inflammatory breast cancerPathological complete responseInflammatory breast cancerNeoadjuvant systemic therapyNon-IBCBreast cancerSystemic therapyEarly-stage human epidermal growth factor receptor 2 (HER2)-positive breast cancerPredictors of pathologic complete responseHuman epidermal growth factor receptor 2 (HER2)-positive breast cancerIBC cohortIBC statusPathologic complete response rateLow axillary burdenNoninflammatory breast cancerTrastuzumab-based chemotherapyTreatment de-escalationPhase II trialClinical-pathological featuresLong-term prognosisPCR scoreAxillary burdenNeoadjuvant trastuzumabPCR rateComplete response
2005
Prognosis after local recurrence after conservative surgery and radiation for early-stage breast cancer
Galper S, Blood E, Gelman R, Abner A, Recht A, Kohli A, Wong JS, Smith D, Bellon J, Connolly J, Schnitt S, Winer E, Silver B, Harris JR. Prognosis after local recurrence after conservative surgery and radiation for early-stage breast cancer. International Journal Of Radiation Oncology • Biology • Physics 2005, 61: 348-357. PMID: 15667952, DOI: 10.1016/j.ijrobp.2004.06.011.Peer-Reviewed Original ResearchConceptsLocal recurrenceConservative surgeryBreast cancerDistant metastasisInitial diagnosisRadiation therapyEarly-stage invasive breast cancerDistant disease-free survivalEarly-stage breast cancerClinical stage IDisease-free survivalFinal study populationInvasive breast cancerLong-term prognosisProportional hazards modelNonbreast malignanciesActuarial freedomMedian followDistant failureSecond malignanciesIpsilateral breastLocal therapyRegional nodalMedian timeStudy population