2000
An electroneutral sodium/bicarbonate cotransporter NBCn1 and associated sodium channel
Choi I, Aalkjaer C, Boulpaep E, Boron W. An electroneutral sodium/bicarbonate cotransporter NBCn1 and associated sodium channel. Nature 2000, 405: 571-575. PMID: 10850716, DOI: 10.1038/35014615.Peer-Reviewed Original ResearchMeSH Keywords4,4'-Diisothiocyanostilbene-2,2'-Disulfonic AcidAnimalsBicarbonatesBiological TransportCarrier ProteinsChloridesCloning, OrganismDNA, ComplementaryElectrophysiologyHumansMolecular Sequence DataRatsRecombinant ProteinsReverse Transcriptase Polymerase Chain ReactionRNA, ComplementarySequence Homology, Amino AcidSodiumSodium ChannelsSodium-Bicarbonate SymportersXenopus
1997
Expression cloning and characterization of a renal electrogenic Na+ /HCO3− cotransporter
Romero M, Hediger M, Boulpaep E, Boron W. Expression cloning and characterization of a renal electrogenic Na+ /HCO3− cotransporter. Nature 1997, 387: 409-413. PMID: 9163427, DOI: 10.1038/387409a0.Peer-Reviewed Original ResearchConceptsPotential membrane-spanning domainsMembrane-spanning domainsElectrogenic sodium bicarbonate cotransporterBinding of inhibitorsSodium bicarbonate cotransporterAnimal cellsBicarbonate transportersElectrogenic transportersSuccessful cloningExpression cloningComplementary DNAPrincipal regulatorAmino acidsBicarbonate cotransporterProtein purificationFunctional familiesXenopus oocytesMolecular informationTransportersCloningReproductive systemSalamander Ambystoma tigrinumProteinAmbystoma tigrinumIntracellular pH
1996
Molecular cloning of a glibenclamide-sensitive, voltage-gated potassium channel expressed in rabbit kidney.
Yao X, Chang AY, Boulpaep EL, Segal AS, Desir GV. Molecular cloning of a glibenclamide-sensitive, voltage-gated potassium channel expressed in rabbit kidney. Journal Of Clinical Investigation 1996, 97: 2525-2533. PMID: 8647945, PMCID: PMC507338, DOI: 10.1172/jci118700.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBrainCloning, MolecularDNA PrimersFemaleGenetic VariationGenomic LibraryGlyburideHumansKidney MedullaKv1.3 Potassium ChannelMiceModels, BiologicalMolecular Sequence DataOocytesPancreatitis-Associated ProteinsPhylogenyPolymerase Chain ReactionPotassium ChannelsPotassium Channels, Voltage-GatedRabbitsRecombinant ProteinsSequence Homology, Amino AcidXenopus laevisConceptsVoltage-gated potassium channelsMolecular cloningFunctional expressionShaker-like potassium channelsPotassium channelsShaker geneGRB-PAP1Novel memberAmino terminusMolecular evidenceShaker channelsAmino acidsXenopus oocytesRabbit kidneyRenal potassium transportCloningGenesPotassium transportChannel clonesFirst reportRabbit brainPotassium conductanceFamilyExpressionKidney