2024
The association between salivary oxytocin, age, and puberty in children with and without OCD
Mora-Jensen A, Clemmensen L, Grønberg M, Lebowitz E, Quintana D, Jørgensen N, Larsen C, Bak L, Christensen G, Pretzmann L, Uhre V, Christensen S, Uhre C, Korsbjerg N, Thoustrup C, Hagstrøm J, Ritter M, Plessen K, Pagsberg A, Lønfeldt N. The association between salivary oxytocin, age, and puberty in children with and without OCD. Scientific Reports 2024, 14: 28693. PMID: 39562644, PMCID: PMC11576962, DOI: 10.1038/s41598-024-80194-8.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderOxytocin concentrationsPediatric obsessive-compulsive disorderSalivary oxytocin concentrationsVisual inspection of plotsOxytocin systemPsychiatric disordersSalivary oxytocinEnzyme-linked immunosorbent assayBehavioral changesPubertal stageAdolescentsModerate supportOxytocinInconsistent resultsPost-hocDisordersChildrenPost hoc testSystem activityCovariates ageParentsAssociationImmunosorbent assayHypothesisPilot study of a parent-based intervention for functional somatic symptoms in children
Etkin R, Winograd S, Calhoun A, Silverman W, Lebowitz E, Shapiro E. Pilot study of a parent-based intervention for functional somatic symptoms in children. Journal Of Pediatric Psychology 2024, jsae092. PMID: 39468777, DOI: 10.1093/jpepsy/jsae092.Peer-Reviewed Original ResearchFunctional somatic symptomsParent-based interventionsSomatic symptomsLevels of functional impairmentWeekly group sessionsPilot studyAssociated with significant distressEvidence-based treatmentsBaseline to posttreatmentGroup sessionsSignificant distressClinical outcomesChildren's symptomsPromote better functioningTreatment satisfactionInterventionBetter functionChild's levelChild careFunctional impairmentClinical researchFollow-upChildrenSymptomsParentsFamily Accommodation and Separation Anxiety: The Moderating Role of Child Attachment
Weeks G, Sakmar E, Clark T, Rose A, Silverman W, Lebowitz E. Family Accommodation and Separation Anxiety: The Moderating Role of Child Attachment. Child Psychiatry & Human Development 2024, 1-10. PMID: 38755332, DOI: 10.1007/s10578-024-01705-2.Peer-Reviewed Original ResearchSeparation anxiety symptomsFamily accommodationAnxiety symptomsAttachment securitySeparation anxietyLevels of attachment securitySeverity of anxiety symptomsAssociated with separation anxietyNo significant moderating effectsClinically anxious childrenAnxiety-related distressHigher attachment securityChild attachment securityFindings enhance understandingAnxious childrenSignificant moderating effectChild anxietyChild attachmentParenting behaviorsAnxietyModerating roleModerating effectSymptomsChildrenAttachmentAttention Training for Child Anxiety and Its Disorders: Moving from Research to Clinical Implementation
Falcone M, Bar-Haim Y, Lebowitz E, Silverman W, Pettit J. Attention Training for Child Anxiety and Its Disorders: Moving from Research to Clinical Implementation. Clinical Child And Family Psychology Review 2024, 27: 550-560. PMID: 38740658, DOI: 10.1007/s10567-024-00482-7.Peer-Reviewed Original ResearchAttention trainingAnxiety reduction effectCognitive neuroscienceChild anxietyComputerized treatmentDelivery of sessionsAnxietyClinical practice settingDisordersEvidence-basedChildrenClinical trial dataPsychoeducationPractice settingsClinical practiceAttentionIncrease accessNeuroscienceTrainingClinical stepsSessionsTrial dataClinical implementationResearchExperimental research
2023
Does Cognitive-Behavioral Therapy for Youth Anxiety Disorders Improve Social Functioning and Peer Relationships?
Etkin R, Juel E, Lebowitz E, Silverman W. Does Cognitive-Behavioral Therapy for Youth Anxiety Disorders Improve Social Functioning and Peer Relationships? Clinical Child And Family Psychology Review 2023, 26: 1052-1076. PMID: 37838627, DOI: 10.1007/s10567-023-00454-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCognitive behavioral therapyAdolescent anxiety disordersPeer relationshipsSocial functioningAnxiety disordersYouth anxiety disordersPeer outcomesAnxiety reductionTreatment-specific effectsFunctioningTreatment specificitySystematic narrative reviewRelated difficultiesSample characteristicsMajority of studiesSpecific outcomesChildrenTreatment outcomesStatistical findingsStudy sampleDisordersNarrative reviewFindingsRelationshipAnxietyAffective Language Spreads Between Anxious Children and Their Mothers During a Challenging Puzzle Task
Nook E, Nardini C, Zacharek S, Hommel G, Spencer H, Martino A, Morra A, Flores S, Anderson T, Marin C, Silverman W, Lebowitz E, Gee D. Affective Language Spreads Between Anxious Children and Their Mothers During a Challenging Puzzle Task. Emotion 2023, 23: 1513-1521. PMID: 36595385, PMCID: PMC10314965, DOI: 10.1037/emo0001203.Peer-Reviewed Original ResearchConceptsNegative affect wordsChallenging puzzle taskAffect wordsAffective languagePuzzle taskEffective emotion regulationSpread of emotionsEmotion regulationNeuroscientific levelAnxious childrenEmotional influencesWord useBidirectional influenceAnxiety disordersBidirectional relationsMother's directionsMental healthEmotionsFuture researchWordsCurrent studyLanguageChildrenTaskMothersThe Role of Pediatric Sensory Over-responsivity and Anxiety Symptoms in the Development of Family Accommodations
Ben-Sasson A, Podoly T, Lebowitz E. The Role of Pediatric Sensory Over-responsivity and Anxiety Symptoms in the Development of Family Accommodations. Child Psychiatry & Human Development 2023, 1-8. PMID: 37219643, DOI: 10.1007/s10578-023-01547-4.Peer-Reviewed Original ResearchFamily accommodationAnxiety symptomsCo-occurring anxiety symptomsSensory Profile 2Elevated anxiety symptomsSOR symptomsChild anxietyGreater symptom severityElevated anxietyEmotional disordersChildren's ImpactIntervention outcomesFamily impactSymptom severityAnxietySensory scaleProfile 2Online surveyChildrenSymptomsStepwise linear regressionAccommodationScoresSensoryFamilyMaternal FGF2 levels associated with child anxiety and depression symptoms through child FGF2 levels
Lebowitz E, Marin C, Orbach M, Salmaso N, Vaccarino F, Silverman W. Maternal FGF2 levels associated with child anxiety and depression symptoms through child FGF2 levels. Journal Of Affective Disorders 2023, 326: 193-197. PMID: 36717031, PMCID: PMC10104478, DOI: 10.1016/j.jad.2023.01.090.Peer-Reviewed Original ResearchConceptsFGF2 levelsDepressive symptomsDepression symptomsChild anxietySymptoms of anxietyRatings of anxietyGrowth factor 2Maternal anxietySymptomsDepressed childrenDepressionChild depressionMothersChildrenFactor 2Self-report ratingsAnxietyIntergenerational pathwaysNon-referred childrenRange of anxietyFGF2AssociationLevelsMaternalChapter 19 Working with parents in the treatment of child and adolescent anxiety
Etkin R, Lebowitz E, Silverman W. Chapter 19 Working with parents in the treatment of child and adolescent anxiety. 2023, 341-358. DOI: 10.1016/b978-0-323-99613-6.00003-x.ChaptersAnxiety treatmentAdolescent anxietyAnxiety disordersChild anxiety treatmentIndividual child treatmentsAdolescent anxiety disordersExtant evidence baseParent variablesTreatment literatureChild's treatmentParent involvementParents' roleTreatment of childrenTheoretical importanceConsiderable methodological variationsEtiology of childrenMethodological variationsAnxietyParentsChildrenInvolvement approachEvidence baseValid inferencesConcrete recommendationsRich literature
2022
De behandeling van angst bij kinderen en jongeren. Op basis van CGT (cognitieve gedragstherapie) en geweldloos verzet
Omer H, Lebowitz E. De behandeling van angst bij kinderen en jongeren. Op basis van CGT (cognitieve gedragstherapie) en geweldloos verzet. 2022 DOI: 10.36254/978-90-8850-997-1.Peer-Reviewed Original ResearchPsychoeducational Interventions
Lebowitz E, Artukoğlu B. Psychoeducational Interventions. 2022, 407-420. DOI: 10.1093/med/9780197543214.003.0024.Peer-Reviewed Original ResearchPsychoeducational interventionParents of childrenRole of psychoeducationSocial victimizationSocial difficultiesPeer victimizationTourette syndromeBetter copingEmotional challengesPsychoeducational resourcesSocial supportPsychoeducationReview researchPsychiatric problemsSchool staffVictimizationNegative stigmaSuch discriminationChildrenDiscriminationCopingIndividualsDisordersInterventionDifficulties
2020
Abnormal asymmetry of thalamic volume moderates stress from parents and anxiety symptoms in children and adolescents with social anxiety disorder
Zhang Y, Liu W, Lebowitz ER, Zhang F, Hu Y, Liu Z, Yang H, Wu J, Wang Y, Silverman WK, Yang Z, Cheng W. Abnormal asymmetry of thalamic volume moderates stress from parents and anxiety symptoms in children and adolescents with social anxiety disorder. Neuropharmacology 2020, 180: 108301. PMID: 32910952, DOI: 10.1016/j.neuropharm.2020.108301.Peer-Reviewed Original ResearchConceptsThalamic volumeThalamic asymmetryAge group differencesAbnormal asymmetryAnxiety disordersBilateral thalamic volumeAnxiety symptomsBrain developmental abnormalitiesOlder age groupsSocial anxiety disorderChronic family stressMedication-free childrenFunctional lateralizationMental disordersAge groupsChronic stressBrain developmentTotal SCARED scoresDisordersFamilial stressChildrenAnxiety severityAdolescentsEmotional disordersDevelopmental abnormalitiesDisparities in Mental and Behavioral Health Treatment for Children and Youth in Immigrant Families
Rosenberg J, Rosenthal MS, Cramer LD, Lebowitz ER, Sharifi M, Yun K. Disparities in Mental and Behavioral Health Treatment for Children and Youth in Immigrant Families. Academic Pediatrics 2020, 20: 1148-1156. PMID: 32599347, PMCID: PMC7655594, DOI: 10.1016/j.acap.2020.06.013.Peer-Reviewed Original ResearchConceptsOdds of receiptBehavioral health servicesBehavioral health treatmentAttention deficit hyperactivity disorder (ADHD) diagnosisPrimary outcomeUnique psychosocial stressorsChild healthHealth treatmentMedicationsHispanic/LatinxHealth servicesPsychosocial stressorsDisorder diagnosisMultiple covariatesTreatmentChildrenNational surveyUS parentsRepresentative surveyHealthSurvey respondentsReceiptDifferencesDiagnosisParent-Child Agreement on Family Accommodation Differentially Predicts Outcomes of Child-Based and Parent-Based Child Anxiety Treatment
Zilcha-Mano S, Shimshoni Y, Silverman WK, Lebowitz ER. Parent-Child Agreement on Family Accommodation Differentially Predicts Outcomes of Child-Based and Parent-Based Child Anxiety Treatment. Journal Of Clinical Child & Adolescent Psychology 2020, 50: 427-439. PMID: 32401557, PMCID: PMC8496486, DOI: 10.1080/15374416.2020.1756300.Peer-Reviewed Original ResearchConceptsParent-child agreementFamily accommodationMultilevel response-surface analysisAnxious Childhood EmotionsChild anxiety treatmentChild anxiety severityCognitive behavioral therapyAnxiety symptom severityDistinct underlying mechanismsChildhood EmotionsChildhood anxietySupportive parentingAnxiety treatmentParent reportBehavioral therapyRole of accommodationAnxiety severityAnxiety disordersPoor treatment outcomesTreatment outcomesSymptom severitySubsequent treatment outcomesTreatment endSignificant predictorsChildrenSPACE, Parent-Based Treatment for Childhood and Adolescent Anxiety: Clinical Case Illustration
Lebowitz E, Majdick J. SPACE, Parent-Based Treatment for Childhood and Adolescent Anxiety: Clinical Case Illustration. Journal Of Cognitive Psychotherapy 2020, 34: 107-118. DOI: 10.1891/jcpsy-d-19-00028.Peer-Reviewed Original ResearchCognitive behavioral therapyParent-based treatmentAnxiety disordersChildhood anxiety disordersClinical case illustrationParental accommodationAdolescent anxietyFamily accommodationChild anxietyChild distressBehavioral therapyParental behaviorSupportive stanceCase illustrationAnxietyEmpirical backgroundDistressEfficacious treatmentOnly interventionTheoretical foundationDisordersCase descriptionParentsChildrenChildhood
2019
Anxious-Irritable Children: A Distinct Subtype of Childhood Anxiety?
Shimshoni Y, Lebowitz ER, Brotman MA, Pine DS, Leibenluft E, Silverman WK. Anxious-Irritable Children: A Distinct Subtype of Childhood Anxiety? Behavior Therapy 2019, 51: 211-222. PMID: 32138933, PMCID: PMC7080292, DOI: 10.1016/j.beth.2019.06.005.Peer-Reviewed Original ResearchFamily Accommodation in Autism Spectrum Disorder
Feldman I, Koller J, Lebowitz ER, Shulman C, Ben Itzchak E, Zachor DA. Family Accommodation in Autism Spectrum Disorder. Journal Of Autism And Developmental Disorders 2019, 49: 3602-3610. PMID: 31134428, DOI: 10.1007/s10803-019-04078-x.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderFamily accommodationSpectrum disorderAnxiety disordersParent-based interventionsFamilies of childrenParents of childrenParental accommodationChild's RRBsRRB severityGreater symptom severityRepetitive behaviorsLower functioningHighlight avenuesPoor treatment outcomesRRBsSymptom severityChildrenMost participantsDisordersTreatment outcomesOCDHigh levelsFunctioningAccommodationParental Predictors of School Attendance Difficulties in Children Referred to an Anxiety Disorders Clinic
Marin C, Anderson T, Lebowitz E, Silverman W. Parental Predictors of School Attendance Difficulties in Children Referred to an Anxiety Disorders Clinic. European Journal Of Education And Psychology 2019, 12: 31-46. DOI: 10.30552/ejep.v12i1.239.Peer-Reviewed Original ResearchSchool attendance difficultiesParental psychological controlFamily accommodationParental depressionPsychological controlParental factorsParental anxietyAttendance difficultiesAnxiety Disorders ClinicAnxious childrenChildhood anxietyChild anxietyImportant predictive roleParent ratingsParental variablesChild depressionBehavior problemsParental predictorsAnxietyChild's ageSignificant predictorsSchool hoursHigh levelsDisorders ClinicChildrenFamily accommodation mediates nightmares and sleep-related problems in anxious children
Lebowitz ER, Shimshoni Y, Silverman WK. Family accommodation mediates nightmares and sleep-related problems in anxious children. Journal Of Anxiety Disorders 2019, 62: 94-99. PMID: 30660831, PMCID: PMC6432767, DOI: 10.1016/j.janxdis.2019.01.004.Peer-Reviewed Original ResearchConceptsSleep-related problemsAnxious childrenFamily accommodationHypothesized mediational pathwaysStructural equation modelingStructural equation modelChildhood anxietyMediational pathwaysFirst empirical evidenceMaternal reportsEquation modelingFit indicesNightmaresEquation modelChildrenEmpirical evidenceEmpirical dataAnxietyAccommodationParticipants
2018
The SPACE program, a parent-based treatment for childhood and adolescent OCD: The case of Jasmine.
Lebowitz ER, Shimshoni Y. The SPACE program, a parent-based treatment for childhood and adolescent OCD: The case of Jasmine. Bulletin Of The Menninger Clinic 2018, 82: 266-287. PMID: 30589579, DOI: 10.1521/bumc.2018.82.4.266.Peer-Reviewed Original ResearchConceptsParent-based treatmentCurrent evidence-based treatmentsCognitive behavioral therapyObsessive-compulsive disorderEvidence-based treatmentsChild avoidFamily accommodationResponse preventionLack of motivationSupportive responsesAdolescent OCDOwn behaviorChildren's symptomsPsychopharmacological treatmentYouthDisordersOCDAdolescentsDistressMotivationCase descriptionTheoretical backgroundParentsSymptomsChildren