1995
Structural Model of the Phospholamban Ion Channel Complex in Phospholipid Membranes
Arkin I, Rothman M, Ludlam C, Aimoto S, Engelman D, Rothschild K, Smith S. Structural Model of the Phospholamban Ion Channel Complex in Phospholipid Membranes. Journal Of Molecular Biology 1995, 248: 824-834. PMID: 7752243, DOI: 10.1006/jmbi.1995.0263.Peer-Reviewed Original ResearchConceptsSelective ion conductanceTransmembrane domainAmino acid residuesN-terminal 30 amino acid residuesAcid residuesCircular dichroismPentameric protein complexFull-length proteinC-terminal 22 amino acid residuesPhospholipid membranesIon channel complexTransmembrane helicesProtein complexesPhosphorylation sitesMembrane proteinsIon conductanceCarboxy terminusHelix bundleIon poreReticulum membraneInhibitory complexLong helixPentameric complexSecondary structureProtein
1984
Neutron scattering shows that cytochrome b5 penetrates deeply into the lipid bilayer
Gogol E, Engelman D. Neutron scattering shows that cytochrome b5 penetrates deeply into the lipid bilayer. Biophysical Journal 1984, 46: 491-495. PMID: 6498267, PMCID: PMC1435021, DOI: 10.1016/s0006-3495(84)84046-1.Peer-Reviewed Original ResearchPositions of proteins S14, S18 and S20 in the 30 S ribosomal subunit of Escherichia coli
Ramakrishnan V, Capel M, Kjeldgaard M, Engelman D, Moore P. Positions of proteins S14, S18 and S20 in the 30 S ribosomal subunit of Escherichia coli. Journal Of Molecular Biology 1984, 174: 265-284. PMID: 6371250, DOI: 10.1016/0022-2836(84)90338-3.Peer-Reviewed Original ResearchMeSH KeywordsEscherichia coliMacromolecular SubstancesModels, BiologicalMonte Carlo MethodNeutronsRibosomal ProteinsRibosomesScattering, Radiation
1981
The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis
Engelman D, Steitz T. The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis. Cell 1981, 23: 411-422. PMID: 7471207, DOI: 10.1016/0092-8674(81)90136-7.Peer-Reviewed Original ResearchConceptsMembrane proteinsSecreted proteinsIntegral membrane proteinsHydrophobic leader peptideSecretion of proteinsHelical hairpinSpecific membrane receptorsPolypeptide sequenceSecond helixLeader peptideTransport proteinsLipid environmentTerminal helixN-terminusSpontaneous insertionMembrane receptorsHairpin structurePolypeptide structureProteinHelixHairpinHydrophobic interiorOnly alphaNonpolar sequencesHydrophobic portion
1980
Neutron diffraction analysis of the structure of rod photoreceptor membranes in intact retinas
Yeager M, Schoenborn B, Engelman D, Moore P, Stryer L. Neutron diffraction analysis of the structure of rod photoreceptor membranes in intact retinas. Journal Of Molecular Biology 1980, 137: 315-348. PMID: 6973637, DOI: 10.1016/0022-2836(80)90319-8.Peer-Reviewed Original Research
1972
A New Method for the Determination of Biological Quarternary Structure by Neutron Scattering
Engelman D, Moore P. A New Method for the Determination of Biological Quarternary Structure by Neutron Scattering. Proceedings Of The National Academy Of Sciences Of The United States Of America 1972, 69: 1997-1999. PMID: 4506067, PMCID: PMC426853, DOI: 10.1073/pnas.69.8.1997.Peer-Reviewed Original ResearchMeSH KeywordsDeuteriumMacromolecular SubstancesModels, BiologicalMolecular WeightNeutronsProteinsRibosomesRNA, Ribosomal
1971
Bilayer Structure in Membranes
WILKINS M, BLAUROCK A, ENGELMAN D. Bilayer Structure in Membranes. Nature 1971, 230: 72-76. PMID: 5279041, DOI: 10.1038/newbio230072a0.Peer-Reviewed Original Research
1969
CURRENT MODELS FOR THE STRUCTURE OF BIOLOGICAL MEMBRANES
Stoeckenius W, Engelman D. CURRENT MODELS FOR THE STRUCTURE OF BIOLOGICAL MEMBRANES. Journal Of Cell Biology 1969, 42: 613-646. PMID: 4895596, PMCID: PMC2107701, DOI: 10.1083/jcb.42.3.613.Peer-Reviewed Original Research
1968
Characterization of the plasma membrane of Mycoplasma laidlawii. IV. Structure and composition of membrane and aggregated components
Engelman D, Morowitz H. Characterization of the plasma membrane of Mycoplasma laidlawii. IV. Structure and composition of membrane and aggregated components. Biochimica Et Biophysica Acta 1968, 150: 385-396. PMID: 5650391, DOI: 10.1016/0005-2736(68)90137-5.Peer-Reviewed Original Research