1992
Forces involved in the assembly and stabilization of membrane proteins1
Cramer W, Engelman D, Von Heijne G, Rees D. Forces involved in the assembly and stabilization of membrane proteins1. The FASEB Journal 1992, 6: 3397-3402. PMID: 1464373, DOI: 10.1096/fasebj.6.15.1464373.Peer-Reviewed Original ResearchMeSH KeywordsCrystallizationElectrochemistryMembrane ProteinsPhotosynthetic Reaction Center Complex ProteinsProtein ConformationConceptsIntegral membrane proteinsHelix-helix interactionsMembrane proteinsIntegral membrane protein complexMembrane protein complexesMembrane-spanning domainsBacterial inner membraneSpecific dimer formationCytochrome b6f complexPolarity of residuesChloroplast thylakoid membranesWater-soluble proteinsProtein complexesReconstitution of bacteriorhodopsinHydrophobic subunitsInner membraneBacterial porinsB6f complexThylakoid membranesSuch polypeptidesBasic residuesProton translocationTrans sidePhotosynthetic reaction centersTrans-membrane orientationBacteriorhodopsin can be refolded from two independently stable transmembrane helices and the complementary five-helix fragment.
Kahn T, Engelman D. Bacteriorhodopsin can be refolded from two independently stable transmembrane helices and the complementary five-helix fragment. Biochemistry 1992, 31: 6144-51. PMID: 1627558, DOI: 10.1021/bi00141a027.Peer-Reviewed Original ResearchConceptsStable transmembrane helixSecond helical segmentX-ray diffractionCovalent connectionAbsorption spectroscopyTwo-dimensional crystalsIndependent folding domainsBacteriorhodopsinHelical segmentsNative structureHelixSpectroscopyPeptidesDiffractionTransmembrane helicesMoleculesCrystalsFragmentsMaterialsStructure
1981
Cholesteryl myristate conformation in liquid crystalline mesophases determined by neutron scattering.
Burks C, Engelman D. Cholesteryl myristate conformation in liquid crystalline mesophases determined by neutron scattering. Proceedings Of The National Academy Of Sciences Of The United States Of America 1981, 78: 6863-6867. PMID: 6947261, PMCID: PMC349152, DOI: 10.1073/pnas.78.11.6863.Peer-Reviewed Original ResearchMeSH KeywordsCholesterol EstersCrystallizationMathematicsMolecular ConformationNeutronsScattering, RadiationConceptsLiquid crystalline mesophasesTerminal methyl groupSpecific molecular modelsCrystalline mesophasesEster moleculesConformational rangeCholesterol moietyPure phaseCholesteryl ester moleculesExtended conformationMethyl groupNeutron scatteringMolecular modelConformationIsotropic phaseThree-carbonMoleculesPersistence of atherosclerosisEstersCholesteryl myristateMesophasesMoiety