2010
Megasomes in Leishmania
McMahon-Pratt D, Ueda-Nakamura T, Traub-Csekö Y. Megasomes in Leishmania. Microbiology Monographs 2010, 17: 131-148. DOI: 10.1007/978-3-642-12863-9_6.Peer-Reviewed Original ResearchImportance of lysosomesProtein traffickingLeishmania virulenceResident enzymesMammalian hostsLysosome-like structuresLeishmania mexicana complexParasite existLysosomal hydrolasesTargeting mechanismCysteine proteinasesSerious public health problemPublic health problemMexicana complexPhlebotomine sandfliesLesion amastigotesGenus LeishmaniaAmastigote formsGood targetClassic pathwayPathwayPromastigote formsHealth problemsMegasomesInsects
2001
Cellular trafficking in trypanosomatids: a new target for therapies?
Costa-Pinto D, Trindade L, McMahon-Pratt D, Traub-Cseko Y. Cellular trafficking in trypanosomatids: a new target for therapies? International Journal For Parasitology 2001, 31: 537-544. PMID: 11334939, DOI: 10.1016/s0020-7519(01)00145-x.Peer-Reviewed Original ResearchConceptsPathogenic trypanosomatidsTrafficking mechanismsLysosomal targetingCellular trafficking mechanismsPlethora of diseasesCellular traffickingTrypanosomatidsTargeting mechanismCysteine proteinasesBiological aspectsNew targetsCurrent knowledgeEfficient vaccineDisease controlTherapyBasic mechanismsTraffickingMechanismTargetParasitesVaccineProteinasesDiseaseTargeting