2024
Biodistribution of Polymeric Nanoparticles following In-Utero Delivery to a Non-Human Primate
Eaton D, Lynn A, Surprenant J, Deschenes E, Guerra M, Rivero R, Yung N, O'Connor M, Glazer P, Bahtiyar M, Saltzman W, Stitelman D. Biodistribution of Polymeric Nanoparticles following In-Utero Delivery to a Non-Human Primate. Biomedicine Hub 2024, 1-16. DOI: 10.1159/000543138.Peer-Reviewed Original ResearchMonogenic diseasesNon-human primatesBiodistribution of polymeric nanoparticlesPreclinical mouse modelsStem cell populationFetal liverFetal malesSystemic deliveryFetal bonesAccumulation of NPIn-uteroMid-gestationNP accumulationBiodistribution studiesPolymeric NPsTherapeutic accessCell populationsMaternal tissuesZone of proliferationPolymeric nanoparticlesDiseaseBirthMiceDeliveryBiodistribution
2004
Mechanism of angiopoietin-1 mediated endothelial progenitor cell recruitment in wound healing
Keswani S, Parvadia J, Stitelman D, Kozin E, Radu A, Alaee D, Zoltick P, Crombleholme T. Mechanism of angiopoietin-1 mediated endothelial progenitor cell recruitment in wound healing. Journal Of The American College Of Surgeons 2004, 199: 60. DOI: 10.1016/j.jamcollsurg.2004.05.124.Peer-Reviewed Original ResearchEPC recruitmentMMP9-/- miceAng-1Control miceWound healingEndothelial progenitor cell recruitmentSerum SCF levelsPotent therapeutic strategyProgenitor cell recruitmentCell recruitmentMMP9 activationSCF supplementationTherapeutic strategiesBone marrowAngiopoietin-1Enhanced neovascularizationEpithelial gapsNeovascularizationEndothelial progenitorsEPC/WoundsHealingSignificant differencesMiceStem cells