1999
Modulation of a pacemaker current through Ca2+-induced stimulation of cAMP production
Lüthi A, McCormick D. Modulation of a pacemaker current through Ca2+-induced stimulation of cAMP production. Nature Neuroscience 1999, 2: 634-641. PMID: 10404196, DOI: 10.1038/10189.Peer-Reviewed Original ResearchConceptsHyperpolarization-activated cation currentIh activationThalamocortical rhythmsThalamocortical activityCation currentNeuronal propertiesPacemaker currentCAMP productionPersistent activationProlonged changesProlonged activationBrief increaseDependent modulationSlow recurrenceActivationSubsequent productionCa2RecurrenceModulation
1998
Periodicity of Thalamic Synchronized Oscillations: the Role of Ca2+-Mediated Upregulation of Ih
Lüthi A, McCormick D. Periodicity of Thalamic Synchronized Oscillations: the Role of Ca2+-Mediated Upregulation of Ih. Neuron 1998, 20: 553-563. PMID: 9539128, DOI: 10.1016/s0896-6273(00)80994-0.Peer-Reviewed Original ResearchConceptsPersistent activationRefractory periodHyperpolarization-activated cation current IhNeural network oscillationsSynchronized network activityWave seizuresRole of Ca2Synchronized dischargesThalamocortical cellsThalamocortical networkElectrophysiological propertiesMediated UpregulationSpindle wavesCurrent IhConstituent neuronsNetwork oscillationsAbnormal patternsActivation curveTime courseNetwork activityUpregulationActivationCritical determinant
1996
What Stops Synchronized Thalamocortical Oscillations?
Bal T, McCormick D. What Stops Synchronized Thalamocortical Oscillations? Neuron 1996, 17: 297-308. PMID: 8780653, DOI: 10.1016/s0896-6273(00)80161-0.Peer-Reviewed Original Research