2012
Human herpesvirus 6 positive Reed–Sternberg cells in nodular sclerosis Hodgkin lymphoma
Siddon A, Lozovatsky L, Mohamed A, Hudnall SD. Human herpesvirus 6 positive Reed–Sternberg cells in nodular sclerosis Hodgkin lymphoma. British Journal Of Haematology 2012, 158: 635-643. PMID: 22757777, DOI: 10.1111/j.1365-2141.2012.09206.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedBlotting, WesternCell Line, TumorDNA, ViralEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHerpesvirus 6, HumanHodgkin DiseaseHumansImmunohistochemistryLymphoma, FollicularMaleMiddle AgedPolymerase Chain ReactionReed-Sternberg CellsRoseolovirus InfectionsSclerosisYoung AdultConceptsNodular sclerosis Hodgkin lymphomaNodular sclerosis HLHHV-6 DNAEpstein-Barr virusHHV-6Hodgkin's lymphomaReed-Sternberg cellsPolymerase chain reactionRS cellsNSHL casesEBV-negative diseaseReactive lymphoid hyperplasiaClassical Hodgkin lymphomaBi-modal age distributionHHV-6 genomeYounger patientsInfectious etiologyLymphoid hyperplasiaPCR positivityYounger ageImmunohistochemistryMost casesConflicting resultsChain reactionCD30
2006
Anatomical mapping of human herpesvirus reservoirs of infection
Chen T, Hudnall SD. Anatomical mapping of human herpesvirus reservoirs of infection. Modern Pathology 2006, 19: 726-737. PMID: 16528368, DOI: 10.1038/modpathol.3800584.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAnal CanalAutopsyCytomegalovirusDNA, ViralFemaleHerpesviridaeHerpesviridae InfectionsHerpesvirus 1, HumanHerpesvirus 2, HumanHerpesvirus 3, HumanHerpesvirus 4, HumanHerpesvirus 6, HumanHerpesvirus 7, HumanHerpesvirus 8, HumanHumansIntestinesMaleMiddle AgedNasal MucosaNervous SystemThyroid GlandConceptsHHV-6Whole blood specimensHSV-1Lymph nodesHHV-7Nasal mucosaAnatomic sitesHuman herpesvirusesHIV-AIDSActive herpesvirus infectionHSV-1 positivitySalivary glandsMajor anatomic sitesMiddle-aged malesTime of deathCardiac arrestHHV-8Adrenal glandElderly malesPrimary infectionHSV-2Urinary bladderHerpesvirus infectionAnatomical mappingBone marrow
2005
Distribution and phenotype of Epstein–Barr virus-infected cells in human pharyngeal tonsils
Hudnall SD, Ge Y, Wei L, Yang NP, Wang HQ, Chen T. Distribution and phenotype of Epstein–Barr virus-infected cells in human pharyngeal tonsils. Modern Pathology 2005, 18: 519-527. PMID: 15696119, DOI: 10.1038/modpathol.3800369.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntigens, CDB-LymphocytesChildChild, PreschoolEpstein-Barr Virus InfectionsEpstein-Barr Virus Nuclear AntigensFemaleGene Expression Regulation, ViralHerpesvirus 4, HumanHumansImmunohistochemistryImmunophenotypingMaleMiddle AgedPalatine TonsilT-LymphocytesViral Matrix ProteinsViral ProteinsConceptsEpstein-Barr virusEBER-positive cellsT cellsHuman tonsilsNK cellsPlasma cellsEpithelial cellsB cellsBiology of EBVNK/T-cell lymphomaEpstein-Barr virus-infected cellsEBV latent protein EBNA1CD20-positive B cellsCD3-positive T cellsEarly Protein BZLF1Non-B cell typeNatural killer cellsRare T cellsT-cell lymphomaLMP1-positive cellsVirus-infected cellsMost tonsilsPlasmacytoid morphologyKiller cellsInterfollicular zones
2004
Hematologic differences in heterophile‐positive and heterophile‐negative infectious mononucleosis
Ventura KC, Hudnall SD. Hematologic differences in heterophile‐positive and heterophile‐negative infectious mononucleosis. American Journal Of Hematology 2004, 76: 315-318. PMID: 15282662, DOI: 10.1002/ajh.20119.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAnimalsAntibodies, HeterophileCattleChildChild, PreschoolCross ReactionsFemaleHerpesvirus 4, HumanHumansInfectious MononucleosisLatex Fixation TestsLeukocyte CountLeukopeniaLymphocyte CountLymphocytesLymphocytosisMaleMiddle AgedRetrospective StudiesConceptsEBV-positive patientsEBV-negative patientsAbsolute lymphocyte countInfectious mononucleosisAtypical lymphocytosisLymphocyte countEpstein-Barr virus infectionEBV-negative casesEBV-negative groupTotal WBC countAgglutination test resultsAtypical lymphocytesAbsolute lymphocytosisBlood countLeukocyte countWBC countHematologic parametersVirus infectionMononucleosisHematologic differencesPatientsLymphocytosisEBVCountCause
2003
Human herpesvirus 8 seroprevalence and viral load in healthy adult blood donors
Hudnall SD, Chen T, Rady P, Tyring S, Allison P. Human herpesvirus 8 seroprevalence and viral load in healthy adult blood donors. Transfusion 2003, 43: 85-90. PMID: 12519435, DOI: 10.1046/j.1537-2995.2003.00272.x.Peer-Reviewed Original ResearchConceptsHHV-8 seroprevalenceBlood donorsDonor bloodPrimary effusion B-cell lymphomaABO blood group BHigh HHV-8 seroprevalenceHuman herpesvirus 8 seroprevalenceLatent HHV-8 antigensHealthy adult blood donorsBlood donor unitsBuffy coat DNAHHV-8 antigensHHV-8 ORF26HHV-8 viremiaSensitive indirect immunofluorescenceGeometric mean titersAdult blood donorsHHV-8 antibodiesHHV-8 DNABlood-borne virusesHuman herpesvirus 8B-cell lymphomaBlood group BDonor blood samplesHuman tumor virus
2000
CD13-positive anaplastic large cell lymphoma of T-cell origin--a diagnostic and histogenetic problem.
Popnikolov N, Payne D, Hudnall S, Hawkins H, Kumar M, Norris B, Elghetany M. CD13-positive anaplastic large cell lymphoma of T-cell origin--a diagnostic and histogenetic problem. Archives Of Pathology & Laboratory Medicine 2000, 124: 1804-8. PMID: 11100061, DOI: 10.5858/2000-124-1804-cpalcl.Peer-Reviewed Original ResearchConceptsExtramedullary myeloid cell tumorAnaplastic large cell lymphomaT-cell originLarge cell lymphomaHistiocytic tumorsCell lymphomaCD30-positive anaplastic large cell lymphomaFlow cytometryExpression of CD13Complete remissionExtranodal sitesCytoplasmic CD3HLA-DRPrognostic implicationsCell tumorsDifferential diagnosisHistiocytic originHistogenetic problemsSurface antigenCD13 expressionVacuolated cytoplasmMalignant transformationCell expressionTumorsSurface markersMarked Increase in L-Selectin–Negative T Cells in Neonatal Pertussis
Hudnall S, Molina C. Marked Increase in L-Selectin–Negative T Cells in Neonatal Pertussis. American Journal Of Clinical Pathology 2000, 114: 35-40. PMID: 10884797, DOI: 10.1309/banx-8jkm-tuqn-4d6p.Peer-Reviewed Original ResearchConceptsPeripheral blood lymphocytesL-selectin expressionT cellsBlood lymphocytesNormal CD4/CD8 ratioCD4/CD8 ratioNaïve T cellsDetailed immunophenotypeNeonatal pertussisCD8 ratioMarked lymphocytosisNK cellsHealthy newbornsHLA-DRLymphoid tissueCord bloodT lymphocytesPertussis toxinB cellsL-selectinLymphocytesFlow cytometryPertussisMarked increaseDramatic findingKikuchi-Fujimoto Disease
Hudnall S. Kikuchi-Fujimoto Disease. American Journal Of Clinical Pathology 2000, 113: 761-764. PMID: 10874874, DOI: 10.1309/n4e2-78v9-qtfh-x4ff.Peer-Reviewed Original ResearchFulminant parvovirus infection following erythropoietin treatment in a patient with acquired immunodeficiency syndrome.
Borkowski J, Amrikachi M, Hudnall S. Fulminant parvovirus infection following erythropoietin treatment in a patient with acquired immunodeficiency syndrome. Archives Of Pathology & Laboratory Medicine 2000, 124: 441-5. PMID: 10705404, DOI: 10.5858/2000-124-0441-fpifet.Peer-Reviewed Original ResearchConceptsAcquired Immunodeficiency SyndromeBone marrow biopsyChronic anemiaImmunodeficiency syndromeMarrow biopsyReticulocyte responseParvovirus infectionErythroid aplasiaSecond bone marrow biopsyHuman parvovirus infectionSevere chronic anemiaIntravenous immunoglobulinErythropoietin treatmentErythroid hyperplasiaErythropoietin administrationRapid correctionHistologic examinationAnemiaInfectious naturePatientsInfectionBiopsyAplasiaSyndromeBlack men
1998
Serologic and Molecular Evidence of Human Herpesvirus 8 Activation in Renal Transplant Recipients
Hudnall S, Rady P, Tyring S, Fish J. Serologic and Molecular Evidence of Human Herpesvirus 8 Activation in Renal Transplant Recipients. The Journal Of Infectious Diseases 1998, 178: 1791-1794. PMID: 9815236, DOI: 10.1086/314482.Peer-Reviewed Original ResearchConceptsRenal transplant patientsGeometric mean titersHealthy adultsTransplant patientsPolymerase chain reactionRenal transplant populationRenal transplant recipientsHIV-positive adultsHuman immunodeficiency virusViral DNATransplant recipientsTransplant groupTransplant populationMean titersImmunodeficiency virusImmunocompromised populationsSerum antibodiesKaposi's sarcomaPositive adultsSerologic resultsIndirect immunofluorescenceWhole bloodChain reactionAdultsPatientsDetection of human herpesvirus-8 DNA in Kaposi’s sarcomas from iatrogenically immunosuppressed patients
Rady P, Hodak E, Yen A, Memar O, Trattner A, Feinmesser M, David M, Hudnall S, Tyring S. Detection of human herpesvirus-8 DNA in Kaposi’s sarcomas from iatrogenically immunosuppressed patients. Journal Of The American Academy Of Dermatology 1998, 38: 429-437. PMID: 9520025, DOI: 10.1016/s0190-9622(98)70501-8.Peer-Reviewed Original ResearchConceptsKaposi's sarcomaHHV-8Polymerase chain reactionHHV-8 DNA detectionImmunosuppressed organ transplant patientsHuman herpesvirus 8 DNAOpen reading frame 26Different primary diseasesHHV-8 sequencesIatrogenic Kaposi's sarcomaOrgan transplant patientsHHV-8 DNAClassic Kaposi's sarcomaEndemic Kaposi's sarcomaFrame 26Nontransplant patientsImmunosuppressive therapyTransplant patientsAIDS-KSPrimary diseaseBiopsy specimensHigh prevalencePatientsNew herpesvirusSarcoma
1997
EBV-associated Kikuchi's histiocytic necrotizing lymphadenitis with cutaneous manifestations
Yen A, Fearneyhough P, Raimer S, Hudnall S. EBV-associated Kikuchi's histiocytic necrotizing lymphadenitis with cutaneous manifestations. Journal Of The American Academy Of Dermatology 1997, 36: 342-346. PMID: 9039215, DOI: 10.1016/s0190-9622(97)80413-6.Peer-Reviewed Original ResearchConceptsHistiocytic necrotizing lymphadenitisKikuchi's histiocytic necrotizing lymphadenitisNecrotizing lymphadenitisCutaneous manifestationsSkin lesionsAtypical lymphoid cellsEBER-1 RNACrusted papulesLymph nodesMalignant lymphomaPathologic findingsKaryorrhectic debrisSerologic studiesPatchy necrosisHistiocytic aggregatesSpontaneous resolutionImmunoperoxidase stainingLymphoid cellsLymphadenitisCausative agentLesionsEBVSitu hybridizationManifestationsMyalgia
1996
MASSIVE PSEUDOLYMPHOMATOUS PERICARDIAL EFFUSION IN THE POSTTRANSPLANT SETTING MIMICKING POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE
Hudnall1 2, Kathleen M, A. G, Yvonne B. MASSIVE PSEUDOLYMPHOMATOUS PERICARDIAL EFFUSION IN THE POSTTRANSPLANT SETTING MIMICKING POSTTRANSPLANT LYMPHOPROLIFERATIVE DISEASE. Transplantation 1996, 61: 1776-1778. PMID: 8685960, DOI: 10.1097/00007890-199606270-00020.Peer-Reviewed Original ResearchConceptsPericardial effusionLymphocytic effusionsLymphoproliferative disordersB-cell lymphoproliferative disordersBenign pericardial effusionCardiac transplant teamPosttransplant lymphoproliferative diseaseCardiac transplant recipientsCell lymphoproliferative disordersImmunosuppressant withdrawalTransplant recipientsTransplant settingLymphoproliferative diseaseTransplant teamOpposite therapyImmunophenotypic dataTransplant processUnusual caseEffusionDetailed histologicDiagnostic distinctionEBVDisordersSpurious automated white cell count wiht Coulter STKS in the myelodysplastic syndromes suggests the presence of a red cell membrane defect
Elghetany M, Hudnall S. Spurious automated white cell count wiht Coulter STKS in the myelodysplastic syndromes suggests the presence of a red cell membrane defect. American Journal Of Hematology 1996, 52: 69-69. PMID: 8638626, DOI: 10.1002/(sici)1096-8652(199605)52:1<69::aid-ajh20>3.0.co;2-1.Peer-Reviewed Original Research
1994
Multiple myeloma after cardiac transplantation: An unusual form of posttransplant lymphoproliferative disorder
Chucrallah A, Crow M, Rice L, Rajagopalan S, Hudnall S. Multiple myeloma after cardiac transplantation: An unusual form of posttransplant lymphoproliferative disorder. Human Pathology 1994, 25: 541-545. PMID: 8200651, DOI: 10.1016/0046-8177(94)90129-5.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, ViralBase SequenceDNA-Binding ProteinsEpstein-Barr Virus Nuclear AntigensGene RearrangementGenes, ImmunoglobulinHeart TransplantationHerpesvirus 4, HumanHumansIn Situ HybridizationLymphoproliferative DisordersMaleMiddle AgedMolecular Sequence DataMultiple MyelomaPolymerase Chain ReactionRNA, ViralConceptsPosttransplant lymphoproliferative disorderPolymerase chain reactionCardiac transplantationLymphoproliferative disordersMonoclonal immunoglobulin heavy chain gene rearrangementEBV-negative casesPast EBV infectionCardiac transplant recipientsImmature plasma cellsImmunoglobulin heavy chain gene rearrangementHeavy chain gene rearrangementChain gene rearrangementCyclosporin withdrawalEBV infectionTransplant recipientsEBER-1Monomorphous populationMultiple myelomaEBV genomePlasma cellsSkull lesionsMyelomaSerum analysisGene rearrangementsChain reaction