2016
Characterizing treatment pathways at scale using the OHDSI network
Hripcsak G, Ryan P, Duke J, Shah N, Park R, Huser V, Suchard M, Schuemie M, DeFalco F, Perotte A, Banda J, Reich C, Schilling L, Matheny M, Meeker D, Pratt N, Madigan D. Characterizing treatment pathways at scale using the OHDSI network. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 7329-7336. PMID: 27274072, PMCID: PMC4941483, DOI: 10.1073/pnas.1510502113.Peer-Reviewed Original ResearchConceptsAdministrative claims dataTreatment pathwaysClaims dataType 2 diabetes mellitusFirst-line medicationElectronic health record dataClinical trial resultsObservational researchHealth record dataElectronic health recordsDiabetes mellitusHypertension patientsDepression patientsConsistent therapyObservational studyOHDSI networkObservational Health Data SciencesPatientsTrial resultsClinical hypothesisHealth recordsRecord dataSignificant heterogeneityHealth Data SciencesHypertension
2015
Symptom trends in the last year of life from 1998 to 2010: a cohort study.
Singer A, Meeker D, Teno J, Lynn J, Lunney J, Lorenz K. Symptom trends in the last year of life from 1998 to 2010: a cohort study. Annals Of Internal Medicine 2015, 162: 175-83. PMID: 25643305, PMCID: PMC4346253, DOI: 10.7326/m13-1609.Peer-Reviewed Original ResearchConceptsProxy reportsPain intensitySymptom prevalenceLife careProxy-reported painChronic lung diseaseCongestive heart failureManagement of painPrevalence of depressionEnd of lifeCohort studySevere painHeart failureLung diseaseObservational studyTroubling symptomsSudden deathIndividual symptomsAlarming symptomsPainFamily respondentsHRS participantsSymptom trendsPrevalenceRepresentative longitudinal survey