2006
Alexithymia and stress-induced brain activation in cocaine-dependent men and women.
Li CS, Sinha R. Alexithymia and stress-induced brain activation in cocaine-dependent men and women. Journal Of Psychiatry And Neuroscience 2006, 31: 115-21. PMID: 16575427, PMCID: PMC1413961.Peer-Reviewed Original ResearchConceptsToronto Alexithymia ScaleFrontal cortexTAS scoresScript-guided imageryAbstinent cocaine-dependent subjectsBilateral temporal cortexFunctional magnetic resonanceStress-induced brain activationProcessing of stressMiddle frontal cortexCocaine-dependent individualsRight frontal cortexCocaine-dependent menCocaine-dependent patientsNeutral imageryNeural processingBrain activationMale cocaine usersStressful situationsCocaine-dependent subjectsRight amygdalaAlexithymic featuresAlexithymia ScaleTemporal cortexSubcortical activation
2005
Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals
Li CS, Milivojevic V, Constable RT, Sinha R. Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals. Psychiatry Research 2005, 140: 271-280. PMID: 16290108, DOI: 10.1016/j.pscychresns.2005.09.002.Peer-Reviewed Original ResearchConceptsPerigenual anterior cingulateAbstinent cocaine-dependent subjectsCocaine-dependent subjectsCannabis abuseCannabis abusersCocaine-dependent individualsAnterior cingulateEmotional stressBOLD signalUrine drug screeningSame statistical thresholdDrug use historyFrontal cortical areasHeavy cannabis useLevel-dependent contrastPrevious neuroimaging studiesFunctional magnetic resonanceFrontal cortexCortical areasAlcohol consumptionCortical activationEmotional stress taskUse of marijuanaBrain regionsDecreased activation