1994
Endothelin-1 conversion and receptor characterization in human placental arteries
Wilkes B, Macica C, Mento P. Endothelin-1 conversion and receptor characterization in human placental arteries. American Journal Of Physiology 1994, 267: e242-e249. PMID: 8074203, DOI: 10.1152/ajpendo.1994.267.2.e242.Peer-Reviewed Original ResearchConceptsFetoplacental blood vesselsEndothelin-1Big endothelin-1Blood vesselsHuman placental arteriesEndothelin receptor subtypesEndothelin-1 receptorsAtrial natriuretic factorTime-dependent increasePlacental arteriesSpecific receptor sitesPerfusion pressureAngiotensin IIEndothelin receptorsNatriuretic factorReceptor subtypesSmall arteriesPlacental cotyledonsPotency orderFmol/High-affinity binding sitesBig endothelinReceptor characterizationScatchard analysisPressor peptide
1991
Localization of endothelin-like immunoreactivity in rat kidneys
Wilkes B, Susin M, Mento P, Macica C, Girardi E, Boss E, Nord E. Localization of endothelin-like immunoreactivity in rat kidneys. American Journal Of Physiology 1991, 260: f913-f920. PMID: 2058711, DOI: 10.1152/ajprenal.1991.260.6.f913.Peer-Reviewed Original ResearchConceptsEndothelin-like immunoreactivityVasa rectaeEndothelin-1Renal papillaRat kidneyProximal tubule brush borderDistal nephron segmentsTubule brush borderNormal rat kidneyGlomerular immunostainingArcuate arteriesPeritubular capillariesRenal cortexRenal tissueImmunoperoxidase techniqueParacrine actionIntense immunostainingCytoplasmic immunostainingDuct epitheliumImmunostaining densityRenal medullaBig endothelinNephron segmentsImmunoreactivityImmunostainingGlomerular endothelin receptors during initiation and maintenance of ischemic acute renal failure in rats
Wilkes B, Pearl A, Mento P, Maita M, Macica C, Girardi E. Glomerular endothelin receptors during initiation and maintenance of ischemic acute renal failure in rats. American Journal Of Physiology 1991, 260: f110-f118. PMID: 1847009, DOI: 10.1152/ajprenal.1991.260.1.f110.Peer-Reviewed Original ResearchConceptsIschemic acute renal failureAcute renal failureRenal blood flowGlomerular filtration rateET receptorsRenal failureEndothelin receptorsET infusionElevated ET levelsLeft renal arteryMean arterial pressureNormal Sprague-Dawley ratsSprague-Dawley ratsReceptor sitesRenal hemodynamicsArterial pressureContralateral kidneyRenal arteryFiltration rateReceptor numberBlood flowET levelsRatsET bindingAdditional studies