2024
S1849 Are Patients With MASH Cirrhosis or Alcohol-Associated Cirrhosis More Likely to Develop Hepatic Hydrothorax? A National Transplant Database Analysis
Boateng S, Zahrawi F, Jalalzai M, Banini B. S1849 Are Patients With MASH Cirrhosis or Alcohol-Associated Cirrhosis More Likely to Develop Hepatic Hydrothorax? A National Transplant Database Analysis. The American Journal Of Gastroenterology 2024, 119: s1331-s1331. DOI: 10.14309/01.ajg.0001036764.22289.36.Peer-Reviewed Original ResearchThe impact of MELD exception points for hydrothorax on posttransplant mortality: a propensity score-matched analysis
Fathma S, Boateng S, Amatya A, Ameyaw P, Banini B. The impact of MELD exception points for hydrothorax on posttransplant mortality: a propensity score-matched analysis. European Journal Of Gastroenterology & Hepatology 2024, 36: 1016-1021. PMID: 38829948, PMCID: PMC11230850, DOI: 10.1097/meg.0000000000002792.Peer-Reviewed Original ResearchUnited Network for Organ SharingEnd-stage liver diseaseHepatic hydrothoraxMELD exception pointsScore matching analysisMELD exceptionsPosttransplant mortalityLiver transplantationComplications of end-stage liver diseaseLiver diseaseChild-Pugh grade CUnited Network for Organ Sharing DatabasMultivariate logistic regressionDecompensated cirrhosisSerum creatinineNo significant differenceTransplant databaseMELD scoreClinical decision-makingNational transplant databaseCombined cohortLaboratory valuesGrade CHydrothoraxPosttransplant deathTu1606 EVOLVING BMI TRENDS IN LIVER TRANSPLANT RECIPIENTS: A 34-YEAR RETROSPECTIVE ANALYSIS (1988-2022)
Boateng S, Zahrawi F, Amatya A, Sanyal A, Banini B. Tu1606 EVOLVING BMI TRENDS IN LIVER TRANSPLANT RECIPIENTS: A 34-YEAR RETROSPECTIVE ANALYSIS (1988-2022). Gastroenterology 2024, 166: s-1359. DOI: 10.1016/s0016-5085(24)03577-7.Peer-Reviewed Original ResearchTu1572 RACIAL DISPARITIES IN HEPATOCELLULAR CARCINOMA BASED ON TUMOR STAGE AT DIAGNOSIS: A NATIONWIDE POPULATION-BASED ANALYSIS USING THE UNITED STATES CANCER STATISTICS (USCS) DATABASE, 2001-2020
Abboud Y, Ismail M, Khan H, Goyal R, Banini B. Tu1572 RACIAL DISPARITIES IN HEPATOCELLULAR CARCINOMA BASED ON TUMOR STAGE AT DIAGNOSIS: A NATIONWIDE POPULATION-BASED ANALYSIS USING THE UNITED STATES CANCER STATISTICS (USCS) DATABASE, 2001-2020. Gastroenterology 2024, 166: s-1735. DOI: 10.1016/s0016-5085(24)04454-8.Peer-Reviewed Original Research136 IMPACT OF PRE-TRANSPLANT MALIGNANCY ON INTESTINAL TRANSPLANT OUTCOMES: AN ANALYSIS OF THE UNITED NETWORK FOR ORGAN SHARING DATABASE
Boateng S, Ameyaw P, Annor E, Watt K, Banini B. 136 IMPACT OF PRE-TRANSPLANT MALIGNANCY ON INTESTINAL TRANSPLANT OUTCOMES: AN ANALYSIS OF THE UNITED NETWORK FOR ORGAN SHARING DATABASE. Gastroenterology 2024, 166: s-1778. DOI: 10.1016/s0016-5085(24)04561-x.Peer-Reviewed Original ResearchAcute Hepatitis due to Primary Human Immunodeficiency Virus Infection
Elliott E, Smith D, Lipscomb J, Banini B, Meurer L, Vanderford T, Johnson J, Jain D, Achhra A. Acute Hepatitis due to Primary Human Immunodeficiency Virus Infection. Open Forum Infectious Diseases 2024, 11: ofae170. PMID: 38585186, PMCID: PMC10996125, DOI: 10.1093/ofid/ofae170.Peer-Reviewed Original ResearchHuman immunodeficiency virusHuman immunodeficiency virus infectionAcute hepatitisPrimary human immunodeficiency virus infectionConsistent with acute hepatitisPrimary human immunodeficiency virusHuman immunodeficiency virus p24 antigenAcute retroviral syndromeImmunodeficiency virus infectionSevere acute hepatitisHIV proviral DNAAcute liver diseaseP24 antigenImmunodeficiency virusLaboratory abnormalitiesSystemic manifestationsRare caseLiver diseaseProviral DNAVirus infectionLiver histopathologyHepatitisCell compartmentParenchymal cellsLiver tissuePulmonary complications of advanced chronic liver diseases: an updated review
Thevenot T, Raevens S, Aujayeb A, Banini B, Cadranel J, DuBrock H. Pulmonary complications of advanced chronic liver diseases: an updated review. Exploration Of Digestive Diseases 2024, 3: 301-325. DOI: 10.37349/edd.2024.00053.Peer-Reviewed Original ResearchPulmonary complicationsHepatopulmonary syndromeLiver transplantationHepatic hydrothoraxAdvanced chronic liver diseasePre-existing lung diseasePathophysiology of HHLack of routine screeningChronic liver diseaseLiver transplant survivalMultidisciplinary team approachPortopulmonary hypertensionCirrhotic populationCurative therapyPortal hypertensionIncreasing dyspneaTherapeutic optionsClinical featuresMELD exception pointsAwaiting transplantationLung diseasePatient populationLiver diseaseComplicationsTransplant survivalChapter 6 Clinical diagnosis and evaluation pathway
Lam R, Banini B, Do A, Lim J. Chapter 6 Clinical diagnosis and evaluation pathway. 2024, 77-100. DOI: 10.1016/b978-0-323-99649-5.00003-0.Peer-Reviewed Original Research
2023
Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
Chen G, Banini B, Do A, Gunderson C, Zaman S, Lim J. Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. Genes 2023, 14: 1811. PMID: 37761951, PMCID: PMC10531443, DOI: 10.3390/genes14091811.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseBiopsy-proven non-alcoholic fatty liver diseaseEffects of exerciseFatty liver diseaseHistological outcomesLiver histologyLiver diseaseClinical trialsHistological endpointsSystematic reviewSignificant histopathological improvementNAFLD activity scoreImpact of exerciseIndependent effectsRandom-effects modelSystematic literature searchHistopathological improvementExercise interventionActivity scoreClinical endpointsPooled estimatesMeta-AnalysisTotal participantsLiterature searchComparison groupNonalcoholic liver disease: Epidemiology, risk factors, natural history, and management strategies
Agyapong G, Dashti F, Banini B. Nonalcoholic liver disease: Epidemiology, risk factors, natural history, and management strategies. Annals Of The New York Academy Of Sciences 2023, 1526: 16-29. PMID: 37400359, PMCID: PMC10524684, DOI: 10.1111/nyas.15012.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNonalcoholic fatty liver diseaseNonalcoholic fatty liverLiver diseaseRisk factorsCommon chronic liver diseaseEnd-stage liver diseaseNatural historyNAFLD risk factorsChronic liver diseaseFatty liver diseaseCurrent management strategiesClinicopathologic spectrumLiver transplantationNonalcoholic steatohepatitisProgressive fibrosisFatty liverHepatocellular cancerLeading indicationDiseaseUnited StatesManagement strategiesCirrhosisSteatohepatitisTransplantationFibrosisPharmacologic Management of Obesity after Liver Transplantation: A Critical Review.
Zahrawi F, Fathma S, Mehal W, Banini B. Pharmacologic Management of Obesity after Liver Transplantation: A Critical Review. Annals Of Gastroenterology And Digestive Disorders 2023, 6: 17-25. PMID: 38098758, PMCID: PMC10719957.Peer-Reviewed Original ResearchNew uses for an old remedy: Digoxin as a potential treatment for steatohepatitis and other disorders
Jamshed F, Dashti F, Ouyang X, Mehal W, Banini B. New uses for an old remedy: Digoxin as a potential treatment for steatohepatitis and other disorders. World Journal Of Gastroenterology 2023, 29: 1824-1837. PMID: 37032732, PMCID: PMC10080697, DOI: 10.3748/wjg.v29.i12.1824.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
The Independent Effect of Exercise on Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review
Chen G, Banini B, Do A, Lim J. The Independent Effect of Exercise on Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review. Clinical And Molecular Hepatology 2022, 29: s319-s332. PMID: 36517000, PMCID: PMC10029942, DOI: 10.3350/cmh.2022.0366.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseBiopsy-proven non-alcoholic fatty liver diseaseNon-invasive testsFatty liver diseaseHepatic steatosisLiver fibrosisLiver diseaseHistological endpointsIndependent effectsSystematic reviewNon-randomized interventional studyMagnetic resonance imaging-based techniquesAdditional large RCTsChronic liver diseaseSignificant histological improvementEffects of exerciseClinical outcome endpointsSystematic literature searchHistological improvementExercise interventionHepatocyte ballooningOriginal research studiesLarge RCTsOutcome endpointsInterventional studyDigoxin as an emerging therapy in noncardiac diseases
Dashti F, Jamshed F, Ouyang X, Mehal W, Banini B. Digoxin as an emerging therapy in noncardiac diseases. Trends In Pharmacological Sciences 2022, 44: 199-203. PMID: 36396496, DOI: 10.1016/j.tips.2022.10.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEditorial: Recent advances in the understanding of hepatocellular carcinogenesis
Banini BA, Mehta R, Santhekadur PK. Editorial: Recent advances in the understanding of hepatocellular carcinogenesis. Frontiers In Oncology 2022, 12: 963998. PMID: 35936725, PMCID: PMC9350505, DOI: 10.3389/fonc.2022.963998.Commentaries, Editorials and LettersHepatic Hydrothorax: An Independent Predictor of Mortality in Cirrhosis? Is the MELD-Na Score Worth Its Salt?
Asotibe JC, Banini BA. Hepatic Hydrothorax: An Independent Predictor of Mortality in Cirrhosis? Is the MELD-Na Score Worth Its Salt? Digestive Diseases And Sciences 2022, 67: 4609-4611. PMID: 35534743, DOI: 10.1007/s10620-022-07523-7.Commentaries, Editorials and LettersDerivation and Validation of a Model to Predict Clinically Significant Portal Hypertension Using Transient Elastography and FIB-4
Banini BA, Patel S, Yu JW, Kang L, Bailey C, Strife BJ, Siddiqui MS, Patel V, Matherly SC, Lee H, Lewis S, Cherian R, Stravitz RT, Luketic V, Sanyal AJ, Sterling RK. Derivation and Validation of a Model to Predict Clinically Significant Portal Hypertension Using Transient Elastography and FIB-4. Journal Of Clinical Gastroenterology 2022, 57: 189-197. PMID: 34999644, PMCID: PMC9271129, DOI: 10.1097/mcg.0000000000001664.Peer-Reviewed Original ResearchConceptsHepatic venous pressure gradientSignificant portal hypertensionFIB-4Chronic liver diseaseAdvanced fibrosisPortal hypertensionLiver biopsyLiver diseasePlatelet countPositive predictive value 27Negative predictive value 99Venous pressure gradientTransjugular liver biopsyGold standardInternal bootstrap validationExternal validationLiver histologyFibrosis indexCurrent gold standardTransient elastographyOptimal cutoffBootstrap validationPatientsSpecificity 67Value 99
2021
Role of candidate gene variants in modulating the risk and severity of alcoholic hepatitis
Beaudoin JJ, Liang T, Tang Q, Banini BA, Shah VH, Sanyal AJ, Chalasani NP, Gawrieh S. Role of candidate gene variants in modulating the risk and severity of alcoholic hepatitis. Alcohol Clinical And Experimental Research 2021, 45: 709-719. PMID: 33616244, PMCID: PMC8076096, DOI: 10.1111/acer.14581.Peer-Reviewed Original ResearchConceptsPatatin-like phospholipase domain-containing protein 3Effects of variantsCopy number variantsAcyltransferase domainDomain-containing protein 3Genetic basisCandidate genesCandidate gene variantsGenetic variantsNumber variantsHaptoglobin geneIndividual variantsProtein 3Member 2AllelesGenesGene variantsRisk allelesTransmembrane 6Affected individualsVariantsIdentification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin‐Like Phospholipase Domain Containing 3–Mediated Acceleration of Steatohepatitis
Banini BA, Kumar DP, Cazanave S, Seneshaw M, Mirshahi F, Santhekadur PK, Wang L, Guan HP, Oseini AM, Alonso C, Bedossa P, Koduru SV, Min H, Sanyal AJ. Identification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin‐Like Phospholipase Domain Containing 3–Mediated Acceleration of Steatohepatitis. Hepatology 2021, 73: 1290-1306. PMID: 33131062, PMCID: PMC8046714, DOI: 10.1002/hep.31609.Peer-Reviewed Original ResearchReply:
Banini BA, Alwatari Y, Ogden N, Gershman E, Shah RD, Strife BJ, Shojaee S, Sterling RK. Reply:. Hepatology 2021, 73: 1237-1238. PMID: 32767857, DOI: 10.1002/hep.31512.Commentaries, Editorials and Letters