2000
Predictors of inactivation and reasons for participant inactivation during a skin cancer chemoprevention study.
Cartmel B, Moon T, Levine N, Rodney S, Alberts D. Predictors of inactivation and reasons for participant inactivation during a skin cancer chemoprevention study. Cancer Epidemiology Biomarkers & Prevention 2000, 9: 999-1002. PMID: 11008922.Peer-Reviewed Original ResearchConceptsCancer chemoprevention trialsChemoprevention trialsSkin cancer chemoprevention studiesFuture chemoprevention trialsIU of retinolCancer chemoprevention studiesLow education levelSkin cancer chemoprevention trialOnly significant predictorPlacebo groupChemoprevention studiesClinical symptomsUnmarried statusCommon reasonStudy capsulesTreatment groupsInactive participantsVitamin AGood complianceFirst monthTrialsSignificant predictorsNumber of participantsSignificant differencesSymptoms
1999
Effects of long-term intake of retinol on selected clinical and laboratory indexes
Cartmel B, Moon T, Levine N. Effects of long-term intake of retinol on selected clinical and laboratory indexes. American Journal Of Clinical Nutrition 1999, 69: 937-943. PMID: 10232634, DOI: 10.1093/ajcn/69.5.937.Peer-Reviewed Original ResearchConceptsRetinol intakeAdverse effectsLaboratory indicesVitamin A/dCoronary artery disease riskCancer chemoprevention trialsLong-term ingestionMinimal adverse effectsLong-term intakeSkin cancer chemoprevention trialAlkaline phosphataseMedian followPlacebo groupChemoprevention trialsClinical symptomsRetinol groupChemopreventive agentsCholesterol concentrationsHealthy populationSkin cancerModerate riskDisease riskIntakeFurther studiesSignificant differences
1997
Effect of retinol in preventing squamous cell skin cancer in moderate-risk subjects: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group.
Moon T, Levine N, Cartmel B, Bangert J, Rodney S, Dong Q, Peng Y, Alberts D. Effect of retinol in preventing squamous cell skin cancer in moderate-risk subjects: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group. Cancer Epidemiology Biomarkers & Prevention 1997, 6: 949-56. PMID: 9367069.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaNew squamous-cell carcinomasModerate-risk subjectsSkin cancerHazard ratioNew nonmelanoma skin cancersSquamous cell skin cancerIU of retinolNew skin cancersPlacebo-supplemented subjectsPrimary end pointNonmelanoma skin cancerFree-living subjectsEffect of retinolMedian followOral retinolBasal cell carcinoma skin cancersActinic keratosesRetinol supplementationCell carcinomaDaily supplementationAdverse symptomsEnd pointCancerNew BCCTrial of retinol and isotretinoin in skin cancer prevention: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group.
Levine N, Moon T, Cartmel B, Bangert J, Rodney S, Dong Q, Peng Y, Alberts D. Trial of retinol and isotretinoin in skin cancer prevention: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group. Cancer Epidemiology Biomarkers & Prevention 1997, 6: 957-61. PMID: 9367070.Peer-Reviewed Original ResearchConceptsCutaneous squamous cell carcinomaSquamous cell carcinomaBasal cell carcinomaNonmelanoma skin cancerCell carcinomaSkin cancerPlacebo-controlled trialHigh-risk subjectsSkin cancer preventionEffect of retinolOral retinolStudy clinicCancer preventionOutcome measuresIsotretinoinBeneficial effectsStudy periodRetinolTrialsCarcinomaCancerPreventionTotal numberParticipantsPlaceboRetinoids in prevention of skin cancer
Moon T, Levine N, Cartmel B, Bangert J. Retinoids in prevention of skin cancer. Cancer Letters 1997, 114: 203-205. PMID: 9103292, DOI: 10.1016/s0304-3835(97)04663-6.Peer-Reviewed Original ResearchConceptsBasal cell skin cancerModerate-risk subjectsPrior skin cancersHigh-risk subjectsRisk subjectsSkin cancerB trialSquamous cell skin cancerSquamous cell cancerEffects of retinoidsActinic keratosesCell cancerClinical trialsIntervention durationCancerTrialsRetinolRetinoidsPlaceboIncidencePreventionSubjectsSignificant benefitsIsotretinoinKeratoses