A meta-study on transcription factor networks in the suicidal brain
Cabrera-Mendoza B, de Anda-Jáuregui G, Nicolini H, Fresno C. A meta-study on transcription factor networks in the suicidal brain. Journal Of Psychiatric Research 2021, 136: 23-31. PMID: 33548827, DOI: 10.1016/j.jpsychires.2021.01.037.Peer-Reviewed Original ResearchConceptsBipolar disorderSchizophrenia NetworkSuicidal brainDifferent mental disordersDisorders NetworkMajor depression disorderImmune response genesGene expression differencesHealthy controlsImmune responseDepression disorderDepression networkDisorder-specific characteristicsMental disordersPrefrontal cortexDisordersExpression differencesRegulatory mechanismsTranscription factor networkSuicideSocial stressBrainSuicide neurobiologyTranscriptional factorsFactor networkBrain Gene Expression Profiling of Individuals With Dual Diagnosis Who Died by Suicide
Cabrera-Mendoza B, Fresno C, Monroy-Jaramillo N, Fries GR, Walss-Bass C, Glahn DC, Ostrosky-Wegman P, Genis-Mendoza AD, Martínez-Magaña JJ, Romero-Pimentel AL, Díaz-Otañez CE, García-Dolores F, González-Sáenz EE, Mendoza-Morales RC, Flores G, Vázquez-Roque R, Nicolini H. Brain Gene Expression Profiling of Individuals With Dual Diagnosis Who Died by Suicide. Journal Of Dual Diagnosis 2019, 16: 177-190. PMID: 31774731, DOI: 10.1080/15504263.2019.1692160.Peer-Reviewed Original ResearchConceptsSubstance use disordersMood disordersDual diagnosisUse disordersMental comorbiditiesGene expression profilesMental disordersSingle disorderCell type enrichmentAdverse clinical outcomesGlial-specific markersMore mental disordersExpression profilesDorsolateral prefrontal cortexClinical outcomesGABAergic neurotransmissionGlial markersHigh riskDisorder patientsComorbiditiesSuicidal behaviorPrefrontal cortexGene expression profilingSynaptic genesDisorders