1999
Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress
Li S, Chen B, Azuma N, Hu Y, Wu S, Sumpio B, Shyy J, Chien S. Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress. Journal Of Clinical Investigation 1999, 103: 1141-1150. PMID: 10207166, PMCID: PMC408275, DOI: 10.1172/jci5367.Peer-Reviewed Original ResearchAnimalsBiological TransportCalcium-Calmodulin-Dependent Protein KinasesCattleCdc42 GTP-Binding ProteinCell Cycle ProteinsCells, CulturedCytoskeletonEndothelium, VascularGTP PhosphohydrolasesGTP-Binding ProteinsIntracellular Signaling Peptides and ProteinsJNK Mitogen-Activated Protein KinasesMitogen-Activated Protein KinasesPhysical StimulationProtein Serine-Threonine KinasesResponse ElementsRho GTP-Binding ProteinsRhoA GTP-Binding ProteinRho-Associated KinasesTranscription Factor AP-1
1996
Involvement of rho p21 in Cyclic Strain-Induced Tyrosine Phosphorylation of Focal Adhesion Kinase (pp125FAK), Morphological Changes and Migration of Endothelial Cells
Yano Y, Saito Y, Narumiya S, Sumpio B. Involvement of rho p21 in Cyclic Strain-Induced Tyrosine Phosphorylation of Focal Adhesion Kinase (pp125FAK), Morphological Changes and Migration of Endothelial Cells. Biochemical And Biophysical Research Communications 1996, 224: 508-515. PMID: 8702419, DOI: 10.1006/bbrc.1996.1057.Peer-Reviewed Original ResearchAdenosine Diphosphate RiboseADP Ribose TransferasesAnimalsAorta, ThoracicBotulinum ToxinsCattleCell Adhesion MoleculesCell MovementCells, CulturedCytoskeletal ProteinsEndothelium, VascularFocal Adhesion Kinase 1Focal Adhesion Protein-Tyrosine KinasesGTP-Binding ProteinsMitomycinsPaxillinPhosphoproteinsPhosphorylationPhosphotyrosineProtein-Tyrosine KinasesRho GTP-Binding ProteinsStress, Mechanical