2003
Antisense basic fibroblast growth factor alters the time course of mitogen-activated protein kinase in arterialized vein graft remodeling
Yamashita A, Hanna AK, Hirata S, Dardik A, Sumpio BE. Antisense basic fibroblast growth factor alters the time course of mitogen-activated protein kinase in arterialized vein graft remodeling. Journal Of Vascular Surgery 2003, 37: 866-873. PMID: 12663990, DOI: 10.1067/mva.2003.130.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood Vessel ProsthesisCell Physiological PhenomenaEndothelium, VascularFibroblast Growth FactorsHyperplasiaJNK Mitogen-Activated Protein KinasesMitogen-Activated Protein KinasesModels, AnimalP38 Mitogen-Activated Protein KinasesProteinsRabbitsRegenerationRNA, AntisenseTime FactorsTransfectionVeinsConceptsProtein kinaseBasic fibroblast growth factorMAPK activationFibroblast growth factorMitogen-activated protein kinase (MAPK) familyC-Jun N-terminal protein kinaseProtein kinase familyExtracellular signal-regulated kinase 1/2Antisense basic fibroblast growth factorMitogen-activated protein kinaseSignal-regulated kinase 1/2Messenger RNA sequencesP38 kinase activationGrowth factor altersMAPK-dependent mechanismFibroblast growth factor activityGrowth factorKinase familyKinase activationGrowth factor activityPhosphorylation of MAPKsKinase 1/2RNA sequencesWestern blot analysisBasic fibroblast growth factor activity
2000
Gender does not impact infrainguinal vein bypass graft outcome
Frangos S, Karimi S, Kerstein M, Harpavat M, Sumpio B, Roberts A, Gahtan V. Gender does not impact infrainguinal vein bypass graft outcome. Surgery 2000, 127: 679-686. PMID: 10840364, DOI: 10.1067/msy.2000.105859.Peer-Reviewed Original ResearchConceptsGraft patencySurvival rateMultivariate analysisInfrainguinal vein bypass graftsCox proportional hazards modelInfrainguinal occlusive diseaseLimb salvage rateVein bypass graftsBypass graft operationsProportional hazards modelLife-table analysisInfrainguinal vein bypassPercentage of womenMajor amputationGraft outcomePostoperative complicationsIncisional complicationsOcclusive diseasePostoperative outcomesLimb salvageRenal diseaseBypass graftPatient selectionVein graftsMorbidity rate
1999
Clinical and Biological Relevance of Vein Cuff Anastomosis
Steinthorsson G, Sumpio B. Clinical and Biological Relevance of Vein Cuff Anastomosis. Acta Chirurgica Belgica 1999, 99: 282-288. PMID: 10674129, DOI: 10.1080/00015458.1999.12098497.Peer-Reviewed Original ResearchConceptsSuitable autologous saphenous veinAutologous saphenous veinAlternative graft materialGraft failureDistal anastomosisCuff anastomosisPTFE graftsFemorodistal bypassSaphenous veinImproved patencyPoor patencyVenous cuffKnee positionPatencyGraft materialProsthetic materialAnastomosisGraftPossible mechanical explanationBiological basisSignificant numberSeries of studiesPatientsBypassCuff