2006
The management of deep sternal wound infections using vacuum assisted closure™ (V.A.C.®) therapy
Fleck T, Gustafsson R, Harding K, Ingemansson R, Lirtzman MD, Meites HL, Moidl R, Price P, Ritchie A, Salazar J, Sjögren J, Song DH, Sumpio BE, Toursarkissian B, Waldenberger F, Wetzel‐Roth W. The management of deep sternal wound infections using vacuum assisted closure™ (V.A.C.®) therapy. International Wound Journal 2006, 3: 273-280. PMID: 17199763, PMCID: PMC7951489, DOI: 10.1111/j.1742-481x.2006.00273.x.Peer-Reviewed Original ResearchConceptsDeep sternal wound infectionSternal wound infectionWound infectionV.A.C. therapyThorough wound irrigationPrinciples of treatmentVacuum-assisted closureTreatment of infectionsSurgical debridementClinical guidelinesEarly recognitionWound irrigationAssisted closureCurrent evidenceSurgical supervisionTherapyInfectionAdequate experienceInternational expertsTreatmentInternational groupDebridementGroupGroup discussionsClinicians
1997
Gene Regulation by Mechanical Forces
Oluwole BO, Du W, Mills I, Sumpio BE. Gene Regulation by Mechanical Forces. Endothelium 1997, 5: 85-93. PMID: 9237042, DOI: 10.3109/10623329709079866.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCattleCell Adhesion MoleculesCell Culture TechniquesCells, CulturedEndothelinsEndothelium, VascularEpoprostenolFocal Adhesion Kinase 1Focal Adhesion Protein-Tyrosine KinasesGene Expression RegulationHemorheologyHumansMechanoreceptorsMembranes, ArtificialNitric OxideProtein-Tyrosine KinasesSignal TransductionStress, MechanicalTissue Plasminogen ActivatorTranscription FactorsTranscription, GeneticVacuumConceptsEndothelial cellsEndothelial cell functionCyclic strainVasoactive mediatorsSecond messenger cascadesNitric oxideBlood vesselsMechanical forcesCell functionMechanical deformationFlow of bloodMessenger cascadesLuminal surfaceSpecific response elementsPromoter geneResponse elementExternal forcesMediatorsCytoskeletal changesCellsForceProstacyclinExpressionTranscription levels
1988
Enhanced Collagen Production by Smooth Muscle Cells During Repetitive Mechanical Stretching
Sumpio BE, Banes AJ, Link WG, Johnson G. Enhanced Collagen Production by Smooth Muscle Cells During Repetitive Mechanical Stretching. JAMA Surgery 1988, 123: 1233-1236. PMID: 3178470, DOI: 10.1001/archsurg.1988.01400340059010.Peer-Reviewed Original ResearchResponse of porcine aortic smooth muscle cells to cyclic tensional deformation in culture
Sumpio B, Banes A. Response of porcine aortic smooth muscle cells to cyclic tensional deformation in culture. Journal Of Surgical Research 1988, 44: 696-701. PMID: 3379947, DOI: 10.1016/0022-4804(88)90103-5.Peer-Reviewed Original Research