2004
Molecular and biological effects of hemodynamics on vascular cells.
Pradhan S, Sumpio B. Molecular and biological effects of hemodynamics on vascular cells. Frontiers In Bioscience-Landmark 2004, 9: 3276-85. PMID: 15353357, DOI: 10.2741/1480.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAtherosclerosisCell MovementCell ProliferationCells, CulturedCyclic AMPDiglyceridesDisease ProgressionEndothelial CellsExtracellular MatrixHemodynamicsHumansInositol 1,4,5-TrisphosphateIntercellular Adhesion Molecule-1Plasminogen ActivatorsProtein Kinase CRisk FactorsStress, MechanicalConceptsEndothelial cellsSignificant atherosclerotic plaqueSystemic risk factorsTissue plasminogen activatorCellular adhesion moleculesCurrent pertinent literatureCultured endothelial cellsRisk factorsSecond messenger systemsSignificant lesionsProtein kinase C pathwayICAM-1Atherosclerosis formationAtherosclerotic plaquesVascular anatomyKinase C pathwayNitric oxideVascular cellsPlasminogen activatorAdhesion moleculesBlood vesselsVascular biologyMessenger systemsVessel wallPertinent literature
2000
Tissue Plasminogen Activator: Biological and Physiological Relevance for Vascular Surgeons
Chang R, Kamal K, Sumpio B. Tissue Plasminogen Activator: Biological and Physiological Relevance for Vascular Surgeons. 2000, 1315-1323. DOI: 10.1007/978-1-4612-1190-7_103.Peer-Reviewed Original ResearchTissue-type plasminogen activatorThrombolytic therapyDeep venous thrombosisOcclusive vascular diseaseEfficacy of treatmentCerebrovascular accidentPulmonary embolismVenous thrombosisClinical outcomesMyocardial infarctionVascular diseaseVascular surgeonsHuman trialsEffective treatmentThrombolytic agentsPlasminogen activatorTherapyPhysiological relevanceTreatmentEndogenous propertiesEmbolismInfarctionThrombosisPatientsAgents