2004
The effect of sex steriods on IL-8 and MCP-1 expression in human endometrial endothelial cells − The gatekeeper of human endometrium
Luk J, Seval Y, Kayisli U, Arici A. The effect of sex steriods on IL-8 and MCP-1 expression in human endometrial endothelial cells − The gatekeeper of human endometrium. Fertility And Sterility 2004, 82: s62. DOI: 10.1016/j.fertnstert.2004.07.158.Peer-Reviewed Original Research
2001
Effect of gonadotropin-releasing hormone agonists on monocyte chemotactic protein-1 production and macrophage infiltration in leiomyomatous uterus
Sozen I, Senturk L, Arici A. Effect of gonadotropin-releasing hormone agonists on monocyte chemotactic protein-1 production and macrophage infiltration in leiomyomatous uterus. Fertility And Sterility 2001, 76: 792-796. PMID: 11591415, DOI: 10.1016/s0015-0282(01)02378-0.Peer-Reviewed Original ResearchConceptsMonocyte chemotactic protein-1Leiomyomatous uterusMacrophage countGonadotropin-releasing hormone agonistDirect paracrine effectChemotactic protein-1 productionMCP-1 levelsChemotactic protein-1MCP-1 stainingCross-sectional studyMyometrium of womenMCP-1 expressionMonocyte chemotactic protein-1 productionMCP-1 protein expressionUniversity Medical CenterProtein-1 productionGnRH agonistHormone agonistMacrophage infiltrationMedical CenterMAIN OUTCOMEImmunohistochemical analysisLeiomyoma cellsParacrine effectsGnRHEstradiol regulates monocyte chemotactic protein-1 in human coronary artery smooth muscle cells: a mechanism for its antiatherogenic effect
Seli E, Selam B, Mor G, Kayisli U, Pehlivan T, Arici A. Estradiol regulates monocyte chemotactic protein-1 in human coronary artery smooth muscle cells: a mechanism for its antiatherogenic effect. Menopause The Journal Of The North American Menopause Society 2001, 8: 296-301. PMID: 11449089, DOI: 10.1097/00042192-200107000-00013.Peer-Reviewed Original ResearchConceptsHuman coronary artery smooth muscle cellsCoronary artery smooth muscle cellsArtery smooth muscle cellsMonocyte chemotactic protein-1Smooth muscle cellsChemotactic protein-1Recruitment of macrophagesMCP-1 expressionMCP-1 proteinMuscle cellsProtective effectProtein 1Arterial wallSelective estrogen receptor modulatorsCoronary smooth muscle cellsMCP-1 protein productionEstrogen's protective effectPhenol red-free mediumCharcoal-stripped calf serumProtein productionEstrogen receptor modulatorsPathogenesis of atherosclerosisReverse transcriptase-polymerase chain reactionNorthern blotLow-density lipoprotein
1999
Regulation of Monocyte Chemotactic Protein-1 Expression in Human Endometrial Stromal Cells by Estrogen and Progesterone1
Arici A, Senturk L, Seli E, Bahtiyar M, Kim G. Regulation of Monocyte Chemotactic Protein-1 Expression in Human Endometrial Stromal Cells by Estrogen and Progesterone1. Biology Of Reproduction 1999, 61: 85-90. PMID: 10377035, DOI: 10.1095/biolreprod61.1.85.Peer-Reviewed Original ResearchConceptsMCP-1 expressionEndometrial stromal cellsHuman endometrial stromal cellsMCP-1 levelsStromal cellsMacrophage migrationEstrogen levelsMCP-1 protein productionMonocyte chemotactic protein-1 expressionMCP-1 mRNA levelsChemotactic protein-1 expressionChemotactic protein-1Combination of E2Steroid hormone levelsProtein-1 expressionConcentration-dependent mannerEndometrial macrophagesMCP-1E2 treatmentHormone levelsSex steroidsEstradiol-17betaProgesteroneMRNA levelsProtein 1
1998
Expression and Hormonal Regulation of Monocyte Chemotactic Protein-1 in Myometrium and Leiomyomata
Sozen I, Olive D, Arici A. Expression and Hormonal Regulation of Monocyte Chemotactic Protein-1 in Myometrium and Leiomyomata. Fertility And Sterility 1998, 69: 1095-1102. PMID: 9627299, DOI: 10.1016/s0015-0282(98)00072-7.Peer-Reviewed Original ResearchConceptsMCP-1 mRNA levelsChemotactic protein-1MCP-1Leiomyoma cellsSex steroidsHigher MCP-1 levelsSteroid hormonesMCP-1 protein productionMonocyte chemotactic protein-1MCP-1 levelsMRNA levelsProtein 1Proliferative phase samplesImmunoreactive MCP-1MCP-1 expressionUniversity Medical CenterLeiomyoma cell proliferationParacrine growth factorMCP-1 mRNAGrowth stimulatory effectMessenger RNA levelsPathogenesis of leiomyomaLocal immunityGnRH analoguesProspective study